[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Increased fat intake, impaired fat oxidation, and failure of fat cell proliferation result in ectopic fat storage, insulin resistance, and type 2 diabetes mellitus

E Ravussin, SR Smith - Annals of the New York Academy of …, 2002 - Wiley Online Library
It is widely accepted that increasing adiposity is associated with insulin resistance and
increased risk of type 2 diabetes. The predominant paradigm used to explain this link is the …

Skeletal muscle mass and distribution in 468 men and women aged 18–88 yr

I Janssen, SB Heymsfield… - Journal of applied …, 2000 - journals.physiology.org
We employed a whole body magnetic resonance imaging protocol to examine the influence
of age, gender, body weight, and height on skeletal muscle (SM) mass and distribution in a …

Estimation of skeletal muscle mass by bioelectrical impedance analysis

I Janssen, SB Heymsfield… - Journal of applied …, 2000 - journals.physiology.org
The purpose of this study was to develop and cross-validate predictive equations for
estimating skeletal muscle (SM) mass using bioelectrical impedance analysis (BIA). Whole …

High-intensity training induces non-stoichiometric changes in the mitochondrial proteome of human skeletal muscle without reorganisation of respiratory chain content

C Granata, NJ Caruana, J Botella, NA Jamnick… - Nature …, 2021 - nature.com
Mitochondrial defects are implicated in multiple diseases and aging. Exercise training is an
accessible, inexpensive therapeutic intervention that can improve mitochondrial …

Sex differences of sarcopenia in an elderly asian population: the prevalence and risk factors

J Hwang, S Park - International Journal of Environmental Research and …, 2022 - mdpi.com
The loss of muscle mass is widespread in age-related health phenomena in the elderly
population. This study examined the prevalence of sarcopenia in a community-dwelling …

What are the physical characteristics associated with a normal metabolic profile despite a high level of obesity in postmenopausal women?

M Brochu, A Tchernof, IJ Dionne… - The Journal of …, 2001 - academic.oup.com
Although obesity is often associated with insulin resistance and a cluster of metabolic
disturbances, the existence of a subgroup of healthy but obese individuals has been …

Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus

L Heilbronn, SR Smith, E Ravussin - International journal of obesity, 2004 - nature.com
BACKGROUND: It is widely accepted that increasing adiposity is associated with insulin
resistance and increased risk of type II diabetes. The predominant paradigm used to explain …

Peroxisome proliferator-activated receptor α activators improve insulin sensitivity and reduce adiposity

M Guerre-Millo, P Gervois, E Raspé, L Madsen… - Journal of Biological …, 2000 - ASBMB
Fibrates and glitazones are two classes of drugs currently used in the treatment of
dyslipidemia and insulin resistance (IR), respectively. Whereas glitazones are insulin …

Link between obesity and type 2 diabetes

A Golay, J Ybarra - Best practice & research Clinical endocrinology & …, 2005 - Elsevier
The relationship between obesity and diabetes is of such interdependence that the term
'diabesity'has been coined. The passage from obesity to diabetes is made by a progressive …