Psychotropic drugs of emerging concerns in aquatic systems: ecotoxicology and remediation approaches

AO Adeola, OT Ore, O Fapohunda, AH Adewole… - Chemistry Africa, 2022 - Springer
Carbamazepine (CBZ) and diazepam (DZP) are often prescribed for the treatment of stress,
muscle spasm, anxiety, alcohol withdrawal symptoms, convulsion, and epileptic conditions …

Antiepileptic drugs in aquatic environments: Occurrence, toxicity, transformation mechanisms and fate

Q Liu, L Wang, X Xu, S Yan, J Zha… - Critical Reviews in …, 2023 - Taylor & Francis
The increasing consumption of antiepileptic drugs (AEDs) has led to their widespread
presence in aquatic environments, which poses a serious threat to human health and …

Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease

H Zhang, J Lu, H Liu, L Guan, S Xu, Z Wang… - Pharmacological …, 2021 - Elsevier
Lipophagy is the autophagic degradation of lipid droplets. Dysregulated lipophagy has been
implicated in the development of non-alcoholic fatty liver disease (NAFLD). Ajugol is an …

Zeolitic imidazolate frameworks as effective crystalline supports for aspergillus-based laccase immobilization for the biocatalytic degradation of carbamazepine

ML Dlamini, M Lesaoana, I Kotze, HL Richards - Chemosphere, 2023 - Elsevier
In this study, zeolitic imidazolate frameworks (ZIF) were employed as effective porous
supports for laccase enzyme attachment and further explored synergistic adsorption and …

Comparison of the toxicity effects of tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) with tributyl phosphate (TNBP) reveals the mechanism of the apoptosis pathway …

S Yan, Q Wang, L Yang, J Zha - Environmental Science & …, 2020 - ACS Publications
To compare the toxicities of a chlorinated and a nonchlorinated organophosphorus flame
retardant (OPFR) in this study, adult calms (Corbicula fluminea) were exposed to tris (1, 3 …

Carbamazepine induces hepatotoxicity in zebrafish by inhibition of the Wnt/β-catenin signaling pathway

Z Bai, K Jia, G Chen, X Liao, Z Cao, Y Zhao… - Environmental …, 2021 - Elsevier
As drug abuse has become increasingly serious, carbamazepine (CBZ) is discharged into
the aquatic environment with municipal sewage, causing potential harm to aquatic …

Carbamazepine at environmentally relevant concentrations caused DNA damage and apoptosis in the liver of Chinese rare minnows (Gobiocypris rarus) by the Ras …

S Yan, R Chen, M Wang, J Zha - Environmental Pollution, 2021 - Elsevier
To assess genetoxicity and the underlying mechanisms of carbamazepine (CBZ) toxicity in
fish, adult Chinese rare minnows (Gobiocypris rarus) were exposed to 1, 10, and 100 μg/L …

[HTML][HTML] Development and Molecular Investigation into the Effects of Carbamazepine Exposure in the Zebrafish (Danio rerio)

H Chen, H Yang, Y Zhao, X Gu… - International Journal of …, 2020 - mdpi.com
Concerns regarding environmental exposures and the impacts of pharmaceuticals on non-
target aquatic organisms continue to increase. The antiepileptic drug carbamazepine (CBZ) …

Effects of carbamazepine in aquatic biota

H Baali, C Cosio - Environmental Science: Processes & Impacts, 2022 - pubs.rsc.org
Carbamazepine (CBZ) is one of the most common pharmaceuticals found in the aquatic
environment. Here, we reviewed studies in aquatic animals highlighting that CBZ affected …

Environmentally relevant concentrations of carbamazepine induced lipid metabolism disorder of Chinese rare minnow (Gobiocypris rarus) in a gender-specific pattern

J Xin, S Yan, X Hong, H Zhang, J Zha - Chemosphere, 2021 - Elsevier
Carbamazepine (CBZ), an anticonvulsant and mood stabilizer, is ubiquitous distributed in
aquatic environment. Though the toxicity and endocrine disrupting effect of CBZ on non …