This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

The last few years have seen major advances in common non-syndromic obesity research,
much of it the result of genetic studies. This Review outlines the competing hypotheses …

It has long been known that there is a genetic component to obesity, and that characterizing
this underlying factor would likely offer the possibility of better intervention in the future …

Recent evidence points to molecules secreted by the adipose tissue, or adipokines, as
possible links between increased adipose mass and metabolic abnormalities. Among these …

The associations of the adiponectin (APM1) gene with parameters of the metabolic
syndrome are inconsistent. We performed a systematic investigation based on fine-mapped …

The metabolic syndrome is a commonly encountered clinical phenotype presenting as
concurrent metabolic abnormalities, including central obesity, dysglycemia, dyslipidemia …

Adiponectin has a variety of metabolic effects on obesity, insulin sensitivity, and
atherosclerosis. To identify genes influencing variation in plasma adiponectin levels, we …

Background Obesity is related to multiple cardiovascular disease (CVD) risk factors as well
as CVD and has a strong familial component. We tested for association between SNPs on …

Several studies have shown that obesity is associated with changes in human brain function
and structure. Since women are more susceptible to obesity than men, it seems plausible …

We analyzed the degree of genetic control over intersubject variability in the microstructure
of cerebral white matter (WM) using diffusion tensor imaging (DTI). We performed heritability …