Emerging histological and serological biomarkers in oral squamous cell carcinoma: Applications in diagnosis, prognosis evaluation and personalized therapeutics

L Pekarek, MJ Garrido‑Gil… - Oncology …, 2023 - spandidos-publications.com
Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity
and accounts for> 90% of all oral cancers. Despite advances in diagnostic procedures and …

Recent advancements, limitations, and future perspectives of the use of personalized medicine in treatment of colon cancer

A Dey, A Mitra, S Pathak, S Prasad… - … in Cancer Research …, 2023 - journals.sagepub.com
Due to the heterogeneity of colon cancer, surgery, chemotherapy, and radiation are
ineffective in all cases. The genomic profile and biomarkers associated with the process are …

Pharmacological impact of microRNAs in head and neck squamous cell carcinoma: prevailing insights on molecular pathways, diagnosis, and nanomedicine …

B Bhattacharjee, AF Syeda, D Rynjah… - Frontiers in …, 2023 - frontiersin.org
Head and neck squamous cell carcinoma is a disease that most commonly produce tumours
from the lining of the epithelial cells of the lips, larynx, nasopharynx, mouth, or oro-pharynx. It …

Effects of saponins from Chinese herbal medicines on signal transduction pathways in cancer: A review

M Zhu, Y Sun, H Bai, Y Wang, B Yang… - Frontiers in …, 2023 - frontiersin.org
Cancer poses a serious threat to human health, and the search for safe and effective drugs
for its treatment has aroused interest and become a long-term goal. Traditional Chinese …

[HTML][HTML] Research progress of nanomaterials in tumor-targeted drug delivery and imaging therapy

LR Fang, YH Wang, ZZ Xiong, YM Wang - OpenNano, 2023 - Elsevier
Cancer continues to threaten people's lives and health, and the number of deaths from
cancer is very high each year. Traditional treatments such as chemotherapy and surgery are …

Platelet membrane-based biochemotactic-targeting nanoplatform combining PDT with EGFR inhibition therapy for the treatment of breast cancer

G Wan, X Chen, R Gou, C Guan, J Chen, Q Wang… - Biomaterials …, 2024 - pubs.rsc.org
Presently, the commonly used anti-tumor drugs lack targeting ability, resulting in a limited
therapeutic efficacy and significant side effects. In this view, platelet membranes (PMs) not …

Design, Synthesis, and Biological Evaluation of Newly Synthesized Cinnamide-Fluorinated Containing Compounds as Bioactive Anticancer Agents

D Nasser Binjawhar, FA Al-Salmi, MA Alghamdi… - ACS …, 2024 - ACS Publications
A new series of cinnamide-fluorinated derivatives has been synthesized and characterized
by using different spectroscopic and elemental microanalyses methods. All of the prepared p …

Cetuximab chemotherapy resistance: Insight into the homeostatic evolution of head and neck cancer

CHDP Diniz, T Henrique, ACB Stefanini… - Oncology …, 2024 - spandidos-publications.com
The complex evolution of genetic alterations in cancer that occurs in vivo is a selective
process involving numerous factors and mechanisms. Chemotherapeutic agents that …

Differential modulation of PI3K/Akt/mTOR activity by EGFR inhibitors: A rationale for co‐targeting EGFR and PI3K in cisplatin‐resistant HNSCC

J Liao, Z Yang, S Azarbarzin, KJ Cullen, H Dan - Head & Neck, 2024 - Wiley Online Library
Purpose To find a new strategy to treat cisplatin‐resistant head and neck squamous cell
carcinoma (HNSCC), we investigated the effects of EGFR inhibitors on the PI3K/Akt/mTOR …

Study protocol: phase II study to evaluate the effect of cetuximab monotherapy after immunotherapy with PD-1 inhibitors in patients with head and neck squamous cell …

KM Burcher, CH Bloomer, E Gavrila… - Therapeutic …, 2024 - journals.sagepub.com
Background: Immunotherapy with programmed death receptor-1 (PD-1) inhibitors, as a
single agent or in combination with chemotherapy, is the standard first-line treatment for …