[HTML][HTML] Regulation of lung epithelial cell senescence in smoking-induced COPD/emphysema by microR-125a-5p via Sp1 mediation of SIRT1/HIF-1a

H Wu, H Ma, L Wang, H Zhang, L Lu… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) affects the health of more than 300 million
people worldwide; at present, there is no effective drug to treat COPD. Smoking is the most …

[HTML][HTML] Chronic obstructive pulmonary disease overdiagnosis and overtreatment: A meta-analysis

M Fiore, M Ricci, A Rosso, ME Flacco… - Journal of Clinical …, 2023 - mdpi.com
This meta-analysis of observational studies aimed at estimating the overall prevalence of
overdiagnosis and overtreatment in subjects with a clinical diagnosis of Chronic Obstructive …

Effects of mixed heavy metals on obstructive lung function: findings from epidemiological and toxicogenomic data

HD Nguyen - Environmental Geochemistry and Health, 2023 - Springer
The molecular mechanisms and associations of mixed heavy metals (lead, mercury, and
cadmium) on obstructive lung function (OLF) in males and females remain unknown. Here …

Lung fibroblasts from chronic obstructive pulmonary disease subjects have a deficient gene expression response to cigarette smoke extract compared to healthy

M Garcia-Ryde, NMD van der Burg… - … journal of chronic …, 2023 - Taylor & Francis
Background and aim Cigarette smoking is the most common cause of chronic obstructive
pulmonary disease (COPD) but more mechanistic studies are needed. Cigarette smoke …

Chronic obstructive pulmonary disease and the modulation of CFTR by acute exposure to cigarette smoke

JW Hanrahan, A Abu-Arish, FH Wong… - … of Physiology-Cell …, 2022 - journals.physiology.org
Chronic obstructive pulmonary disease (COPD) is a leading cause of death and cigarette
smoke is the main risk factor. Detecting its earliest stages and preventing a decline in lung …

Bufei Yishen formula inhibits the cell senescence in COPD by up-regulating the ZNF263 and Klotho expression

W Wang, S Zhang, L Cui, Y Chen, X Xu… - International Journal of …, 2023 - Taylor & Francis
Background Bufei Yishen formula (BYF) is an effective prescription for the clinical treatment
of chronic obstructive pulmonary disease (COPD). However, the molecular mechanism by …

Clinical characteristics of non-smoking chronic obstructive pulmonary disease patients: findings from the KOCOSS cohort

JY Choi, JW Kim, YH Kim, KH Yoo… - COPD: Journal of …, 2022 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) has been regarded as a disease of
smokers, but the prevalence of non-smoking COPD patients have been reported to be …

A nomogram for predicting the risk of pulmonary hypertension for patients with chronic obstructive pulmonary disease

N Wang, Z Guo, X Gong, S Kang, Z Cui… - International Journal of …, 2022 - Taylor & Francis
Background Pulmonary hypertension (PH) is a life-threatening complication of chronic
obstructive pulmonary disease (COPD). Timely diagnosis of PH in COPD patients is vital to …

Performance of COPD population screener questionnaire in COPD screening: a validation study and meta-analysis

Y Gu, Y Zhang, Q Wen, Y Ouyang, Y Shen, H Yu… - Annals of …, 2021 - Taylor & Francis
This study aimed to validate the chronic obstructive pulmonary disease (COPD) Population
Screener (COPD-PS) questionnaire as a screening tool in a cohort of Chinese subjects who …

Korelasi Sesak Napas Dengan Obstruksi Saluran Napas pada Pasien Penyakit Paru Obstruktif Kronik

R Khairani, S Qalbiyah - Jurnal Penelitian Dan Karya Ilmiah …, 2022 - e-journal.trisakti.ac.id
Abstract Latar Belakang: Penyakit paru obstruktif kronik (PPOK) merupakan penyakit
inflamasi kronik saluran napas yang dapat menyebabkan obstruksi saluran napas dan …