Management of active tuberculosis in adults with HIV

G Meintjes, JCM Brust, J Nuttall, G Maartens - The Lancet HIV, 2019 - thelancet.com
Every year, about 1 million people living with HIV worldwide develop tuberculosis. Although
the drug regimens used to treat tuberculosis in these patients are the same as those used in …

Addressing TB-related mortality in adults living with HIV: a review of the challenges and potential solutions

A Sullivan, RR Nathavitharana - Therapeutic Advances in …, 2022 - journals.sagepub.com
Tuberculosis (TB) is the leading cause of death in people living with HIV (PLHIV) globally,
causing 208,000 deaths in PLHIV in 2019. PLHIV have an 18-fold higher risk of TB, and …

[HTML][HTML] In silico design of a promiscuous chimeric multi-epitope vaccine against Mycobacterium tuberculosis

BT Andongma, Y Huang, F Chen, Q Tang… - Computational and …, 2023 - Elsevier
Tuberculosis (TB) is a global health threat, killing approximately 1.5 million people each
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …

[HTML][HTML] Risk factors for mortality among patients diagnosed with multi-drug resistant tuberculosis in Uganda-a case-control study

E Kizito, J Musaazi, K Mutesasira… - BMC infectious …, 2021 - Springer
Abstract Background The World Health Organization (WHO) End TB strategy aims to reduce
mortality due to tuberculosis (TB) to less than 5% by 2035. However, mortality due to …

[HTML][HTML] Subclinical tuberculosis among adults with HIV: clinical features and outcomes in a South African cohort

KL Bajema, IV Bassett, SM Coleman, D Ross… - BMC infectious …, 2019 - Springer
Background Subclinical tuberculosis is an asymptomatic disease phase with important
relevance to persons living with HIV. We describe the prevalence, clinical characteristics …

[HTML][HTML] An inflammatory story: antibodies in tuberculosis comorbidities

MR McLean, LL Lu, SJ Kent, AW Chung - Frontiers in immunology, 2019 - frontiersin.org
Mycobacterium tuberculosis (Mtb) resides in a quarter of the world's population and is the
causative agent for tuberculosis (TB), the most common infectious reason of death in …

Determinants of treatment outcomes in patients with multidrug-resistant TB

E Burhan, PZ Soepandi, F Isbaniah… - … of Tuberculosis and …, 2022 - ingentaconnect.com
BACKGROUND: Treating multidrug-resistant TB (MDR-TB) remains challenging. However,
the determinants and timing of poor outcomes during MDR-TB treatment are still poorly …

Impact of diagnostic strategies for tuberculosis using lateral flow urine lipoarabinomannan assay in people living with HIV

Cochrane Infectious Diseases Group… - Cochrane Database …, 1996 - cochranelibrary.com
Background Tuberculosis is the primary cause of hospital admission in people living with
HIV, and the likelihood of death in the hospital is unacceptably high. The Alere Determine …

[HTML][HTML] Tuberkulose im Erwachsenenalter

T Schaberg, F Brinkmann, C Feiterna-Sperling… - …, 2022 - thieme-connect.com
Die Tuberkulose ist in Deutschland eine seltene, überwiegend gut behandelbare
Erkrankung. Weltweit ist sie eine der häufigsten Infektionserkrankungen mit ca. 10 Millionen …

Long-term safety and impact of immune recovery in heavily treatment-experienced adults receiving fostemsavir for up to 5 years in the phase 3 BRIGHTE study

JM Llibre, JA Aberg, S Walmsley, J Velez… - Frontiers in …, 2024 - frontiersin.org
Introduction Fostemsavir is a gp120-directed attachment inhibitor approved for heavily
treatment-experienced (HTE) adults with multidrug-resistant HIV-1. We provide detailed …