The pre-clinical phase of rheumatoid arthritis: from risk factors to prevention of arthritis
N Petrovská, K Prajzlerová, J Vencovský, L Šenolt… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease considered as a multistep
process spanning from the interaction of genetic (eg, shared epitope or non-HLA loci) …
process spanning from the interaction of genetic (eg, shared epitope or non-HLA loci) …
[HTML][HTML] Transformation of fibroblast‐like synoviocytes in rheumatoid arthritis; from a friend to foe
Swelling and the progressive destruction of articular cartilage are major characteristics of
rheumatoid arthritis (RA), a systemic autoimmune disease that directly affects the synovial …
rheumatoid arthritis (RA), a systemic autoimmune disease that directly affects the synovial …
[HTML][HTML] Academic Textbook: The Role of Melatonin in Pathogenesis and Treatment of Autoimmune Diseases
SOH Tabatabaei, R Moazamiyanfar, AM Fard… - Kindle, 2022 - preferpub.org
An association of melatonin levels with age disease initiation of autoimmune diseases and
pineal calcification was reported while an inverse association between melatonin levels and …
pineal calcification was reported while an inverse association between melatonin levels and …
Synovial fibroblasts as potential drug targets in rheumatoid arthritis, where do we stand and where shall we go?
Fibroblast-like synoviocytes or synovial fibroblasts (FLS) are important cellular components
of the inner layer of the joint capsule, referred to as the synovial membrane. They can be …
of the inner layer of the joint capsule, referred to as the synovial membrane. They can be …
Destructive roles of fibroblast-like synoviocytes in chronic inflammation and joint damage in rheumatoid arthritis
Fibroblast-like synoviocytes (FLSs) are important non-immune cells located mostly in the
inner layer of the synovium. Indeed, these cells are specialized mesenchymal cells …
inner layer of the synovium. Indeed, these cells are specialized mesenchymal cells …
[HTML][HTML] Epigenomic and transcriptomic analyses reveal differences between low-grade inflammation and severe exhaustion in LPS-challenged murine monocytes
Emerging studies suggest that monocytes can be trained by bacterial endotoxin to adopt
distinct memory states ranging from low-grade inflammation to immune exhaustion. While …
distinct memory states ranging from low-grade inflammation to immune exhaustion. While …
Fibroblast pathology in inflammatory joint disease
Rheumatoid arthritis is an immune‐mediated inflammatory disease in which fibroblasts
contribute to both joint damage and inflammation. Fibroblasts are a major cell constituent of …
contribute to both joint damage and inflammation. Fibroblasts are a major cell constituent of …
Clematichinenoside AR inhibits the pathology of rheumatoid arthritis by blocking the circPTN/miR-145-5p/FZD4 signal axis
X Wang, D Zhou, W Zhou, J Liu, Q Xue, Y Huang… - International …, 2022 - Elsevier
Abstract Backgrounds Traditional Chinese medicine roots and rhizomes of Clematis
chinensis Osbeck (CCO) has the effect of improving rheumatoid arthritis (RA) …
chinensis Osbeck (CCO) has the effect of improving rheumatoid arthritis (RA) …
Long noncoding RNA/circular RNA regulates competitive endogenous RNA networks in rheumatoid arthritis: molecular mechanisms and traditional Chinese medicine …
J Wen, J Liu, L Wan, F Wang - Annals of medicine, 2023 - Taylor & Francis
Rheumatoid arthritis (RA) is a systemic and autoimmune disease that is mainly featured
abnormal fibroblast-like synoviocyte (FLS) proliferation and inflammatory cell infiltration …
abnormal fibroblast-like synoviocyte (FLS) proliferation and inflammatory cell infiltration …
Involvements of long noncoding RNAs in obesity‐associated inflammatory diseases
SN Wijesinghe, T Nicholson, K Tsintzas… - Obesity …, 2021 - Wiley Online Library
Obesity is associated with chronic low‐grade inflammation that affects the phenotype of
multiple tissues and therefore is implicated in the development and progression of several …
multiple tissues and therefore is implicated in the development and progression of several …