Fear and anxiety-related disorders are highly prevalent psychiatric conditions characterized
by avoidant and fearful reactions towards specific stimuli or situations, which are …

Histamine is a conserved neuromodulator in mammalian brains and critically involved in
many physiological functions. Understanding the precise structure of the histaminergic …

In this review, we describe the experimental paradigms used in preclinical studies to unravel
the histaminergic brain circuits that modulate the formation and retrieval of memories …

Schisandra chinensis (Turcz.) Baill., as a Chinese functional food, has been widely used in
neurological disorders including insomnia and Alzheimer's disease. The treatment of …

Retrieval represents a dynamic process that may require neuromodulatory signaling. Here,
we report that the integrity of the brain histaminergic system is necessary for retrieval of …

Histaminergic afferent system of the cerebellum, having been considered as an essential
component of the direct hypothalamocerebellar circuits, originates from the …

Histamine has long been accepted as a pro-cognitive agent. However, lines of evidence
have suggested that the roles of histamine in learning and memory processes are much …

Histaminergic fibers are present in the molecular and granular layers of the cerebellum and
have a high density in the vermis and flocullus. Evidence supports that the cerebellar …

Aim Although cognitive deficits commonly co‐occur with stress‐related emotional disorders,
effect of procognitive drugs such as histaminergic H3 receptor antagonists are scarcely …

Rationale Evidence indicates that histamine (HA) modulates learning and memory in
different types of behavioral tasks; however, the exact nature of this modulation and its …