One of the leading killer diseases that target the parenchymal tissues of lungs is
Tuberculosis. Although antimycobacterial drugs are available, there are increased …

Single nucleotide polymorphisms (SNPs) are widely used in genome-wide association
studies and population genetics analyses. Next-generation sequencing (NGS) has become …

Abstract Most Mycobacterium tuberculosis (Mtb) resistant to rifampicin (RIF) has mutations in
the rpoB gene, while most Mtb resistant to isoniazid (INH) has mutations in the katG gene or …

One of predominant contributors to global mortality is tuberculosis (TB), an infection caused
by Mycobacterium tuberculosis (MTB). Inappropriate and ineffectual treatment can lead to …

Tuberculosis (TB) remains one of the most devastating infectious diseases worldwide. The
burden of TB is alarmingly high in developing countries, where diagnosis latent TB infection …

Background While rifampicin (RFP) and isoniazid (INH) are the most commonly used first-
line antituberculosis drugs, multidrug resistance in Mycobacterium tuberculosis poses a …

Study design: To explore the diagnostic value of 3 methods for sputum smear-negative and
non-sputum patients with suspected pulmonary tuberculosis (TB). Methods: This prospective …

Background Mycobacterium tuberculosis complex (MTBC) isolates are typically stored at−
70° C in cryovials containing 1 mL aliquots of a liquid medium, with or without 50% glycerol …

Background: Rapid and accurate detection of drug resistance in Mycobacterium tuberculosis
is critical for effective control of tuberculosis (TB). Herein, we established a novel, low cost …

Background: Tuberculosis (TB) has raised major global health concerns, especially for that
caused by drug-resistant Mycobacterium tuberculosis (M. tuberculosis). The control of TB …