[HTML][HTML] Liver-on-chips for drug discovery and development

V Mehta, G Karnam, V Madgula - Materials Today Bio, 2024 - Elsevier
Recent FDA modernization act 2.0 has led to increasing industrial R&D investment in
advanced in vitro 3D models such as organoids, spheroids, organ-on-chips, 3D bioprinting …

Fibrosis in Chronic Kidney Disease: Pathophysiology and Therapeutic Targets

AB Reiss, B Jacob, A Zubair, A Srivastava… - Journal of Clinical …, 2024 - mdpi.com
Chronic kidney disease (CKD) is a slowly progressive condition characterized by decreased
kidney function, tubular injury, oxidative stress, and inflammation. CKD is a leading global …

DLM–GelMA/tumor slice sandwich structured tumor on a chip for drug efficacy testing

W Hu, HP Bei, H Jiang, D Wu, X Yu, X Zhou, Q Sun… - Lab on a Chip, 2024 - pubs.rsc.org
The in vitro recapitulation of tumor microenvironment is of great interest to preclinical
screening of drugs. Compared with culture of cell lines, tumor organ slices can better …

Reduction of Taylor dispersion in a capillary by spin-up flow—Theoretical insights

Z Larbi, F Larachi, A Azzi - Chemical Engineering Journal, 2024 - Elsevier
We have developed a theoretical framework to characterize the transport and mixing of a
passive scalar in a capillary tube. In this configuration, a suspension of magnetic …