Holding it together: DNA end synapsis during non-homologous end joining
JJ Loparo - DNA repair, 2023 - Elsevier
DNA double strand breaks (DSBs) are common lesions whose misrepair are drivers of
oncogenic transformations. The non-homologous end joining (NHEJ) pathway repairs the …
oncogenic transformations. The non-homologous end joining (NHEJ) pathway repairs the …
The DNA binding domain and the C-terminal region of DNA Ligase IV specify its role in V (D) J recombination
V Malashetty, A Au, J Chavez, M Hanna, J Chu… - Plos one, 2023 - journals.plos.org
DNA Ligase IV is responsible for the repair of DNA double-strand breaks (DSB), including
DSBs that are generated during V (D) J recombination. Like other DNA ligases, Ligase IV …
DSBs that are generated during V (D) J recombination. Like other DNA ligases, Ligase IV …
Recent insights into eukaryotic double-strand DNA break repair unveiled by single-molecule methods
Genome integrity and maintenance are essential for the viability of all organisms. A wide
variety of DNA damage types have been described, but double-strand breaks (DSBs) stand …
variety of DNA damage types have been described, but double-strand breaks (DSBs) stand …