Cognitive impairment in Parkinson's disease: epidemiology, clinical profile, protective and risk factors

P Gonzalez-Latapi, E Bayram, I Litvan, C Marras - Behavioral Sciences, 2021 - mdpi.com
Cognitive impairment is a common non-motor symptom in Parkinson's Disease (PD) and an
important source of patient disability and caregiver burden. The timing, profile and rate of …

Current insights into the risks of using melatonin as a treatment for sleep disorders in older adults

C Tuft, E Matar, Z Menczel Schrire… - … interventions in aging, 2023 - Taylor & Francis
Exogenous melatonin is commonly used for sleep disorders in older adults, and its use is
increasing over time. It appears to have modest efficacy in treating insomnia and circadian …

Widening the spectrum of risk factors, comorbidities, and prodromal features of Parkinson disease

A Schrag, J Bohlken, L Dammertz, S Teipel… - JAMA …, 2023 - jamanetwork.com
Importance The prodromal phase of Parkinson disease (PD) may last for more than 10
years. Recognition of the spectrum and occurrence of risk factors, comorbidities, and …

[HTML][HTML] The effects of synbiotic supplementation on oxidative stress markers, mental status, and quality of life in patients with Parkinson's disease: a double-blind …

S Mehrabani, F Khorvash, Z Heidari… - Journal of Functional …, 2023 - Elsevier
Researches show that the pathogenesis of Parkinson's disease (PD) is influenced by
oxidative stress. This randomized controlled trial investigated the effect of 12 weeks of …

'Anxious fluctuators'a subgroup of Parkinson's disease with high anxiety and problematic on-off fluctuations

GM Pontone, KM Perepezko, JT Hinkle, JJ Gallo… - Parkinsonism & related …, 2022 - Elsevier
Anxiety that occurs in association with on-off dopamine medication fluctuations is a major
cause of distress, dysfunction, and lower quality of life in people with Parkinson's disease …

Acupuncture improves sleep disorders and depression among patients with Parkinson's disease: a meta-analysis

WT Hsu, CM Hsu, SC Hung, SY Hung - Healthcare, 2023 - mdpi.com
Parkinson's disease (PD) is associated with a range of non-motor symptoms that lack
effective treatments. Acupuncture is a popular alternative therapy for PD patients that has …

Dealing with the diagnosis of Parkinson's disease and its implications for couple functioning in the early stage: An interpretative phenomenological analysis

E Wawrziczny, B Flinois, E Constant, E Brugallé… - Plos one, 2024 - journals.plos.org
Background For couples facing Parkinson's disease, marital relationships are significantly
impacted, even at the early stages of the disease. However, very few studies have explicitly …

Gender differences in non-motor fluctuations in Parkinson's disease

G Donzuso, CE Cicero, E Vinciguerra, R Sergi… - Journal of Neural …, 2023 - Springer
Non-motor symptoms (NMS) and Non-motor fluctuations (NMF) in Parkinson's Disease (PD)
are common, involving several domains and affecting quality of life. Aim of the study is to …

The chronic use of serotonin norepinephrine reuptake inhibitors facilitates dyskinesia priming in early Parkinson's disease

M Marano, A Pilotto, A Padovani, D Gupta… - Journal of …, 2024 - Springer
Background Parkinson's disease (PD) patients are frequently exposed to antidepressant
medications (ADMs). Norepinephrine (NE) and serotonin (5HT) systems have a role in …

The Gut Dysmotility Questionnaire for Parkinson's disease: Insights into development and pretest studies

V Raeder, L Batzu, R Untucht, A Fehre, A Rizos… - Frontiers in …, 2023 - frontiersin.org
Objective A total of 48% of patients with Parkinson's disease (PD) present symptoms of
gastrointestinal dysfunction, particularly constipation. Furthermore, gastrointestinal tract …