The molecular and cellular basis of copper dysregulation and its relationship with human pathologies

MT Maung, A Carlson, M Olea‐Flores… - The FASEB …, 2021 - Wiley Online Library
Copper (Cu) is an essential micronutrient required for the activity of redox‐active enzymes
involved in critical metabolic reactions, signaling pathways, and biological functions …

Stimuli‐responsive metal complexes for biomedical applications

I Amarsy, S Papot, G Gasser - … Chemie International Edition, 2022 - Wiley Online Library
Metal‐based compounds have been widely used for biomedical applications. Their unique
characteristics make them attractive for both therapeutic and diagnostic purposes. However …

[HTML][HTML] Metal-based compounds containing selenium: An appealing approach towards novel therapeutic drugs with anticancer and antimicrobial effects

S Ramos-Inza, D Plano, C Sanmartín - European Journal of Medicinal …, 2022 - Elsevier
In recent years, both metal-based complexes and selenium-containing compounds have
been widely explored for their therapeutic properties due to their roles in biological …

Siderophores for medical applications: imaging, sensors, and therapeutics

D Fan, Q Fang - International Journal of Pharmaceutics, 2021 - Elsevier
Siderophores are low-molecular-weight chelators produced by microorganisms to scavenge
iron from the environment and deliver it to cells via specific receptors. Tremendous …

Coumarin-modified ruthenium complexes by disrupting bacterial membrane to combat Gram-positive bacterial infection

HY Huang, P Wang, W Deng, LX Dou, XW Liao… - Dalton …, 2023 - pubs.rsc.org
Antibiotic abuse has caused the generation of drug-resistant bacteria and a series of
infections induced by multidrug-resistant bacteria have become a threat to human health …

[HTML][HTML] Therapeutic Perspectives of Metal Nanoformulations

T Islam, MM Rahaman, MN Mia, I Ara, MT Islam… - Drugs and Drug …, 2023 - mdpi.com
In recent decades, acceptance of nanoparticles (NPs) in therapeutic applications has
increased because of their outstanding physicochemical features. By overcoming the …

[HTML][HTML] Dinuclear iron complexes of iminopyridine-based ligands as selective cytotoxins for tumor cells and inhibitors of cancer cell migration

J Castro, M Bravo, M Albertí, A Marsal… - Pharmaceutics, 2022 - mdpi.com
A family of dinuclear iron (II) compounds with iminopyridine-based ligands displays selective
cytotoxic activity against cancer cell lines. All compounds have IC50 values 2–6 fold lower …

Deciphering the Significance of Metal Ions in the Pathogenesis of Alzheimer's Disease and Forging Pathways Towards Prospective Therapeutic Strategies

L JunYi, Y Wang, B Liu, X Dong, W Cai… - Authorea …, 2023 - essopenarchive.org
Alzheimer's disease (AD), a neurodegenerative condition, is characterized by its progressive
cognitive decline, which includes memory impairment, language alterations, visuospatial …

Study of bacterial conjugation from a practical and fundamental perspective

A Reuter - 2021 - theses.hal.science
Microbial communities are composed of various bacterial species capable of exchanging
genetic information through horizontal gene transfer mechanisms. Among these, bacterial …