Many approaches have been used in the effective management of type 2 diabetes mellitus.
A recent paradigm shift has focused on the role of adipose tissues in the development and …

Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

Autophagy (self‐eating) is a conserved catabolic homeostatic process required for cellular
metabolic demands by removal of the damaged molecules and organelles and for …

Adipose tissue (AT) is classified based on its location, physiological and functional
characteristics. Although there is a clear demarcation of anatomical and molecular features …

Brown adipose tissue (BAT)-mediated thermogenesis declines with age. However, the
underlying mechanism remains unclear. Here we reveal that bone marrow-derived pro …

Thermogenesis is the production of heat that occurs in all warm-blooded animals. During
cold exposure, there is obligatory thermogenesis derived from body metabolism as well as …

Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy
expenditure, has been extensively studied as a potential avenue to combat obesity …

Obesity-associated metabolic abnormalities comprise a cluster of conditions including
dyslipidemia, insulin resistance, diabetes and cardiovascular diseases that has affected …

Adipose tissue eosinophils (ATEs) are important in the control of obesity-associated
inflammation and metabolic disease. However, the way in which ageing impacts the …

The increased worldwide prevalence of obesity, insulin resistance, and their related
metabolic complications have prompted the scientific world to search for new possibilities to …