Shikonin is the major bioactive component extracted from the roots of Lithospermum
erythrorhizon which is also known as “Zicao” in Traditional Chinese Medicine (TCM). Recent …

Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …

One of the leading global causes of death is cancer; even though several treatment methods
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …

Lifestyle is an important factor in health, and researchers are trying to see the adverse effect
on human health of a change in lifestyle. Many people follow unhealthy lifestyles, which …

Ethnopharmacological relevance Zicao is the dried root of Lithospermum erythrorhizon Sieb,
et Zucc, Arnebia euchroma (Royle) Johnst, or Arnebia guttata Bunge and commonly used to …

PAI-1 plays significant roles in cancer occurrence, relapse and multidrug resistance and is
highly expressed in tumours. ACT001, which is currently in phase I clinical trials for the …

Shikonin is a natural compound isolated from herbs and traditional medicines that have
been used in a number of countries to treat various illnesses including inflammation, virus …

Fucoxanthin is rich in seaweed and considered as effective anti-cancer drug because of
powerful antioxidant properties. The objective of this study was to investigate the role of …

Glioblastoma multiforme is one of the most deadly malignant tumors, with more than 10,000
cases recorded annually in the United States. Various clinical analyses and studies show …

Glioblastoma (GBM) is one of the most aggressive malignant tumors with an overall dismal
survival averaging one year despite multimodality therapeutic interventions including …