Yellow fever, the original viral haemorrhagic fever, was one of the most feared lethal
diseases before the development of an effective vaccine. Today the disease still affects as …

Tick-borne encephalitis (TBE) is one of the most dangerous human infections occurring in
Europe and many parts of Asia. The etiological agent Tick-borne encephalitis virus (TBEV) …

Japanese encephalitis (JE) is an infectious disease of the central nervous system caused by
Japanese encephalitis virus (JEV), a zoonotic mosquito-borne flavivirus. JEV is prevalent in …

Japanese encephalitis (JE) is the leading form of viral encephalitis in Asia. It is caused by
the JE virus (JEV), which belongs to the family Flaviviridae. JEV is endemic to many parts of …

Japanese encephalitis (JE) is a serious public health concern in most of Asia. The disease is
caused by JE virus (JEV), a flavivirus transmitted by Culex mosquitoes. Several vaccines …

Dengue viruses (DENV), West Nile virus (WNV) and Japanese encephalitis virus (JEV) are
major global health and growing medical problems. While a live-attenuated vaccine exists …

To construct chimeric YF/DEN viruses (ChimeriVax-DEN), the premembrane (prM) and
envelope (E) genes of yellow fever (YF) 17D virus were replaced with those of each wild …

We previously reported construction of a chimeric yellow fever-dengue type 2 virus
(YF/DEN2) and determined its safety and protective efficacy in rhesus monkeys (F …

ABSTRACT A chimeric yellow fever (YF)-dengue type 2 (dengue-2) virus (ChimeriVax-D2)
was constructed using a recombinant cDNA infectious clone of a YF vaccine strain (YF 17D) …

Although viruses in the genus Flavivirus share complex antigenic interrelationships, they
can be divided into four phylogenetic/ecological groups: two mosquito-borne groups, a tick …