Most patients diagnosed with head and neck squamous cell carcinoma (HNSCC) will
present with locally advanced disease, requiring multimodality therapy. While this approach …

Background Sinonasal neoplasms, whether benign and malignant, pose a significant
challenge to clinicians and represent a model area for multidisciplinary collaboration in …

Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor originating in the
nasopharynx and has a high incidence in Southeast Asia and North Africa. To develop these …

Clinical trials frequently include multiple end points that mature at different times. The initial
report, typically on the based on the primary end point, may be published when key planned …

Importance Induction or adjuvant chemotherapy with concurrent chemoradiotherapy (CCRT)
are first-line treatment options for treatment of locoregionally advanced nasopharyngeal …

Importance Capecitabine maintenance therapy improves survival outcomes in various
cancer types, but data are limited on the efficacy and safety of capecitabine maintenance …

Emerging evidence indicates that DNA methylation plays an important role in the initiation
and progression of nasopharyngeal carcinoma (NPC). DNAJA4 is hypermethylated in NPC …

Nasopharyngeal carcinoma (NPC) is a severe malignancy arising from the nasopharyngeal
epithelium and is southern China's third most common cancer. With the advancement of …

Background Patients with N2–3 nasopharyngeal carcinoma have a high risk of treatment
being unsuccessful despite the current practice of using a concurrent adjuvant cisplatin …

Background Anti-PD-1 therapy and chemotherapy is a recommended first-line treatment for
recurrent or metastatic nasopharyngeal carcinoma, but the role of PD-1 blockade remains …