Conserved and differing functions of the endocrine system across different social systems–oxytocin as a case study

MJ Sosnowski, SF Brosnan - Frontiers in Endocrinology, 2024 - frontiersin.org
A key goal of the field of endocrinology has been to understand the hormonal mechanisms
that drive social behavior and influence reactions to others, such as oxytocin. However, it …

Oxytocin modulates local topography of human functional connectome in healthy men at rest

D Martins, O Dipasquale, Y Paloyelis - Communications Biology, 2021 - nature.com
Oxytocin has recently received remarkable attention for its role as a modulator of human
behaviour. Here, we aimed to expand our knowledge of the neural circuits engaged by …

Navigating Central Oxytocin Transport: Known Realms and Uncharted Territories

D Parmaksiz, Y Kim - The Neuroscientist, 2024 - journals.sagepub.com
Complex mechanisms govern the transport and action of oxytocin (Oxt), a neuropeptide and
hormone that mediates diverse physiologic processes. While Oxt exerts site-specific and …

Brain areas affected by intranasal oxytocin show higher oxytocin receptor expression

PC Habets, C Mclain, OC Meijer - European Journal of …, 2021 - Wiley Online Library
Neuroimaging studies suggest that intranasal oxytocin (IN‐OXT) may modulate emotional
and social processes by altering neural activity patterns. The extent of brain penetration after …

Intranasal oxytocin interacts with testosterone reactivity to modulate parochial altruism

BR Cherki, E Winter, D Mankuta, S Zerbib… - Communications …, 2024 - nature.com
The neuropeptide hormone oxytocin and the steroid hormone testosterone have received
attention as modulators of behavior in the context of intergroup conflict. However, to date …

Neuroimaging genetics of oxytocin: A transcriptomics-informed systematic review

D Prata, M Silva - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
The last couple of decades have witnessed a rapid accumulation of studies implicating
oxytocin (OT) in several neurobiological underpinnings of human behaviour and their …

Design of a randomized clinical trial of brief couple therapy for PTSD augmented with intranasal oxytocin

LM Sippel, TR Wachsman, ME Kelley, KC Knopp… - Contemporary Clinical …, 2024 - Elsevier
Background Leveraging military veterans' intimate relationships during treatment has the
potential to concurrently improve posttraumatic stress disorder (PTSD) symptoms and …

The nanotechnological approach for nasal delivery of peptide drugs: a comprehensive review

C Zuglianello, E Lemos-Senna - Journal of Microencapsulation, 2022 - Taylor & Francis
This review gathers recent studies, patents, and clinical trials involving the nasal
administration of peptide drugs to supply a panorama of developing nanomedicine …

Pharmacokinetics of Intranasal Drugs, Still a Missed Opportunity?

ML Sardu, I Poggesi - Xenobiotica, 2024 - Taylor & Francis
The intranasal (IN) route of administration is important for topical drugs and drugs intended
to act systemically. More recently, direct nose-to-brain input was considered to bypass the …

Oxytocin-trust link in oxytocin-sensitive participants and those without autistic traits

H Kurokawa, Y Kinari, H Okudaira… - Frontiers in …, 2021 - frontiersin.org
There have been numerous studies in which the biological role of oxytocin in trusting
behavior has been investigated. However, a link between oxytocin and trust in humans was …