Oral manifestations of human papillomavirus infections
S Syrjänen - European journal of oral sciences, 2018 - Wiley Online Library
Papillomaviruses are one of the oldest viruses known, dating back 330 million years. During
this long evolution, human papillomaviruses (HPV) have developed into hijackers of human …
this long evolution, human papillomaviruses (HPV) have developed into hijackers of human …
[HTML][HTML] Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer
L Zhou, Q Qiu, Q Zhou, J Li, M Yu, K Li, L Xu… - Nature …, 2022 - nature.com
Integration of human papillomavirus (HPV) DNA into the human genome is considered as a
key event in cervical carcinogenesis. Here, we perform comprehensive characterization of …
key event in cervical carcinogenesis. Here, we perform comprehensive characterization of …
Abortive Infection of Animal Cells: What Goes Wrong
A Embry, DB Gammon - Annual Review of Virology, 2024 - annualreviews.org
Even if a virus successfully binds to a cell, defects in any of the downstream steps of the viral
life cycle can preclude the production of infectious virus particles. Such abortive infections …
life cycle can preclude the production of infectious virus particles. Such abortive infections …
HPV integration generates a cellular super-enhancer which functions as ecDNA to regulate genome-wide transcription
Human papillomavirus (HPV) integration is a critical step in cervical cancer development;
however, the oncogenic mechanism at the genome-wide transcriptional level is still poorly …
however, the oncogenic mechanism at the genome-wide transcriptional level is still poorly …
[HTML][HTML] Multi-omics characterization of silent and productive HPV integration in cervical cancer
J Fan, Y Fu, W Peng, X Li, Y Shen, E Guo, F Lu, S Zhou… - Cell Genomics, 2023 - cell.com
Cervical cancer (CC) that is caused by high-risk human papillomavirus (HPV) remains a
significant public health problem worldwide. HPV integration sites can be silent or actively …
significant public health problem worldwide. HPV integration sites can be silent or actively …
[HTML][HTML] DNA Polymerase alpha is essential for intracellular amplification of hepatitis B virus covalently closed circular DNA
Persistent hepatitis B virus (HBV) infection relies on the establishment and maintenance of
covalently closed circular (ccc) DNA, a 3.2 kb episome that serves as a viral transcription …
covalently closed circular (ccc) DNA, a 3.2 kb episome that serves as a viral transcription …
Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers
DE Symer, K Akagi, HM Geiger, Y Song, G Li… - Genome …, 2022 - genome.cshlp.org
Human papillomavirus (HPV) causes 5% of all cancers and frequently integrates into host
chromosomes. The HPV oncoproteins E6 and E7 are necessary but insufficient for cancer …
chromosomes. The HPV oncoproteins E6 and E7 are necessary but insufficient for cancer …
Insights into the mechanisms and structure of breakage-fusion-bridge cycles in cervical cancer using long-read sequencing
I Rodriguez, NM Rossi, AG Keskus, Y Xie… - The American Journal of …, 2024 - cell.com
Cervical cancer is caused by human papillomavirus (HPV) infection, has few approved
targeted therapeutics, and is the most common cause of cancer death in low-resource …
targeted therapeutics, and is the most common cause of cancer death in low-resource …
[HTML][HTML] Recurrent integration of human papillomavirus genomes at transcriptional regulatory hubs
A Warburton, TE Markowitz, JP Katz, JM Pipas… - NPJ Genomic …, 2021 - nature.com
Oncogenic human papillomavirus (HPV) genomes are often integrated into host
chromosomes in HPV-associated cancers. HPV genomes are integrated either as a single …
chromosomes in HPV-associated cancers. HPV genomes are integrated either as a single …
Multi‐omics data reveals novel impacts of human papillomavirus integration on the epigenomic and transcriptomic signatures of cervical tumorigenesis
X Zeng, Y Wang, B Liu, X Rao, C Cao… - Journal of Medical …, 2023 - Wiley Online Library
Integration of human papilloma virus (HPV) DNA into the human genome may progressively
contribute to cervical carcinogenesis. To explore how HPV integration affects gene …
contribute to cervical carcinogenesis. To explore how HPV integration affects gene …