Rationale: There are no randomized controlled trials comparing different oxygenation
targets for intensive care unit (ICU) patients. Objectives: To determine whether a …

Physiological closed-loop controlled medical devices automatically adjust therapy delivered
to a patient to adjust a measured physiological variable. In critical care scenarios, these …

Abstract Background and Objective Oxygen therapy has become a standard care for the
treatment of patients with chronic obstructive pulmonary disease and other hypoxemic …

This paper presents the implementation of the first fully integrated pulse oximeter front-end
with a power consumption lower than 1 mW. This is enabled by system-and block-level …

Remote sensing of physiological parameters could be a cost effective approach to improving
health care, and low-power sensors are essential for remote sensing because these sensors …

The development of ambulatory arterial pulse oximetry is key to longer term monitoring and
treatment of cardiovascular and respiratory conditions. The investigation presented in this …

The present study aimed to assess the effect of conservative (permissive hypoxaemia)
versus conventional (normoxaemia) protocol for oxygen supplementation on outcome of …

Treatment guidelines are mainly based on randomised clinical trials that include a small and
highly selected fraction of the COPD population [2]. Therefore, it is questionable as to …

This work focuses on the design of low-power fully-integrated pulse oximeter front-ends and
transimpedance amplifiers. Mathematical modelling and numerical simulations are …

In this paper an investigation of the gain, delay, and time-constant parameters of the transfer
function describing the relation between fraction of inspired oxygen (FiO 2) and oxygen …