[HTML][HTML] Immunosuppressive cells in oncolytic virotherapy for glioma: challenges and solutions

J Liu, R Piranlioglu, F Ye, K Shu, T Lei… - Frontiers in Cellular …, 2023 - frontiersin.org
Glioblastoma is a highly aggressive form of brain cancer characterized by the abundance of
myeloid lineage cells in the tumor microenvironment. Tumor-associated macrophages and …

[HTML][HTML] Deciphering immune microenvironment and cell evasion mechanisms in human gliomas

S Rafii, S Kandoussi, A Ghouzlani, O Naji… - Frontiers in …, 2023 - frontiersin.org
Gliomas are considered one of the most malignant cancers in the body. Despite current
therapies, including surgery, chemotherapy, and radiotherapy, these tumors usually recur …

[HTML][HTML] TMT quantitative proteomics reveals key proteins relevant to microRNA-1-mediated regulation in osteoarthritis

P Jiang, D Liang, H Wang, R Zhou, X Che, L Cong… - Proteome Science, 2023 - Springer
Osteoarthritis (OA) is the second-commonest arthritis, but pathogenic and regulatory
mechanisms underlying OA remain incompletely understood. Here, we aimed to identify the …

[HTML][HTML] Microglia depletion reduces human neuronal APOE4-driven pathologies in a chimeric Alzheimer's disease model

A Rao, N Chen, MJ Kim, J Blumenfeld, O Yip, Y Hao… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Despite strong evidence supporting the involvement of both apolipoprotein E4 (APOE4) and
microglia in Alzheimer's Disease (AD) pathogenesis, the effects of microglia on neuronal …

[HTML][HTML] High expression of P4HA3 in obesity: a potential therapeutic target for type 2 diabetes

L Zhuang, C Li, X Hu, Q Yang, X Pei… - Brazilian Journal of …, 2022 - SciELO Brasil
The aims of the present study were to evaluate the expression of prolyl 4-hydroxylase
subunit alpha 3 (P4HA3) in adipocytes and adipose tissue and to explore its effect on …

[HTML][HTML] Intrinsic and Microenvironmental Drivers of Glioblastoma Invasion

E De Fazio, M Pittarello, A Gans, B Ghosh… - International journal of …, 2024 - mdpi.com
Gliomas are diffusely infiltrating brain tumors whose prognosis is strongly influenced by their
extent of invasion into the surrounding brain tissue. While lower-grade gliomas present more …

Study the Roles of Apoe and Microglia in Alzheimer's Disease Using a Chimeric Mouse Model

A Rao - 2023 - search.proquest.com
Despite strong evidence supporting the involvement of both apolipoprotein E4 (APOE4) and
microglia in Alzheimer's Disease (AD) pathogenesis, the effects of microglia on neuronal …

Investigating the Roles of APOE and Microglia in Alzheimer's Disease Using a Chimeric Mouse Model

AT Rao - 2023 - escholarship.org
Despite strong evidence that apolipoprotein E4 (APOE4) increases Alzheimer's Disease
(AD) risk, the etiology and relevant cell types behind human-specific APOE4-related AD …

Physiological Study of Microglial Cell Polarization

J Sun - MEDS Basic Medicine, 2023 - clausiuspress.com
Microglia play an important role in the course of ICH (Intracerebral Hemorr-Hage), and its
activation degree, phenotypic polarization, hematoma clearance mechanism and its …