Parkinson's disease (PD) is a common age-related neurodegenerative disorder whose
pathogenesis is not completely understood. Mitochondrial dysfunction and increased …

The underlying pathophysiology of Parkinson's disease is complex, but mitochondrial
dysfunction has an established and prominent role. This is supported by an already large …

Parkinson's disease (PD) is one of the common long-term degenerative disorders that
primarily affect motor systems. Gastrointestinal (GI) symptoms are common in individuals …

Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons.
Exercise has been reported to slow the clinical progression of PD. We evaluated the …

Neurodegeneration is among the most critical challenges that involve modern societies and
annually influences millions of patients worldwide. While the pathophysiology of Parkinson's …

Psychiatric and neurodegenerative diseases, including major depression disorder (MDD),
bipolar disorder, and Alzheimer's disease, are a burden to society. Deficits of adult …

Background: Prior studies suggest that exercise may prevent movement disorders in
Parkinson's disease (PD) patients. In this meta-analysis, the pooled effect of exercise on PD …

GLP-1 agonists have become increasingly interesting as a new Parkinson's disease (PD)
clinical treatment strategy. Additional preclinical studies are important to validate this …

Alpha-synucleinopathies, such as Parkinson's disease, dementia with Lewy bodies and
multiple system atrophy, are characterized by aberrant accumulation of alpha-synuclein and …

Background: Parkinson's disease is a complicated, gradually progressive neurological
illness characterized by locomotor and non-motor symptomatology that impedes daily …