Heterogeneity in gastric cancer: from pure morphology to molecular classifications

I Gullo, F Carneiro, C Oliveira, GM Almeida - Pathobiology, 2018 - karger.com
Gastric cancer (GC) represents a global health concern. Despite advances in prevention,
diagnosis, and therapy, GC is still the third leading cause of cancer mortality worldwide, with …

Nature meets nurture: molecular genetics of gastric cancer

AN Milne, F Carneiro, C O'morain, GJA Offerhaus - Human genetics, 2009 - Springer
The immensity of genes and molecules implicated in gastric carcinogenesis is
overwhelming and the relevant importance of some of these molecules is too often unclear …

[图书][B] WHO classification of tumours of the digestive system.

FT Bosman, F Carneiro, RH Hruban, ND Theise - 2010 - cabidigitallibrary.org
This book is the third volume of the 4th Edition of the WHO series on histological and genetic
typing of human tumours. It is an authoritative, concise reference book providing an …

Lack of microRNA‐101 causes E‐cadherin functional deregulation through EZH2 up‐regulation in intestinal gastric cancer

J Carvalho, NC van Grieken, PM Pereira… - The Journal of …, 2012 - Wiley Online Library
E‐cadherin expression disruption is commonly observed in metastatic epithelial cancers
and is a crucial step in gastric cancer (GC) initiation and progression. As aberrant …

Genomic profile analysis of diffuse-type gastric cancers

YS Lee, YS Cho, GK Lee, S Lee, YW Kim, S Jho… - Genome biology, 2014 - Springer
Background Stomach cancer is the third deadliest among all cancers worldwide. Although
incidence of the intestinal-type gastric cancer has decreased, the incidence of diffuse-type is …

Genetic and epigenetic alteration in gastric carcinogenesis

C Resende, A Ristimäki, JC Machado - Helicobacter, 2010 - Wiley Online Library
Gastric cancer (GC) is an important cause of morbidity and mortality worldwide. In addition to
environmental factors, genetic factors also play an important role in GC etiology, as …

[HTML][HTML] The PD-1, PD-L1 expression and CD3+ T cell infiltration in relation to outcome in advanced gastric signet-ring cell carcinoma, representing a potential …

S Jin, B Xu, L Yu, Y Fu, H Wu, X Fan, J Wei, B Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Recent data supports a potentially significant role for immune checkpoint inhibitors in the
treatment of gastric cancer. However, there are few data on the clinical implications of …

Epstein-Barr virus-specific methylation of human genes in gastric cancer cells

JL Ryan, RJ Jones, SC Kenney, AG Rivenbark… - Infectious agents and …, 2010 - Springer
Abstract Background Epstein-Barr Virus (EBV) is found in 10% of all gastric
adenocarcinomas but its role in tumor development and maintenance remains unclear. The …

[HTML][HTML] Histotype-based prognostic classification of gastric cancer

AM Chiaravalli, C Klersy, A Vanoli… - World journal of …, 2012 - ncbi.nlm.nih.gov
AIM: To test the efficiency of a recently proposed histotype-based grading system in a
consecutive series of gastric cancers. METHODS: Two hundred advanced gastric cancers …

[HTML][HTML] Early-onset gastric cancer: Learning lessons from the young

AN Milne, GJA Offerhaus - World journal of gastrointestinal …, 2010 - ncbi.nlm.nih.gov
There is by no means a clear-cut pattern of mutations contributing to gastric cancers, and
gastric cancer research can be hampered by the diversity of factors that can induce gastric …