Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis
VC Ardi, TA Kupriyanova… - Proceedings of the …, 2007 - National Acad Sciences
Several lines of evidence have implicated matrix metalloproteinase 9 (MMP-9) as a protease
inducing an angiogenic switch critical for tumor progression. Among MMP-9-expressing cell …
inducing an angiogenic switch critical for tumor progression. Among MMP-9-expressing cell …
Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium
Granulomas, organized aggregates of immune cells, are a hallmark of tuberculosis and
have traditionally been thought to restrict mycobacterial growth. However, analysis of …
have traditionally been thought to restrict mycobacterial growth. However, analysis of …
Biomimetic nanoengineered scaffold for enhanced full-thickness cutaneous wound healing
N Zandi, B Dolatyar, R Lotfi, Y Shallageh… - Acta biomaterialia, 2021 - Elsevier
Wound healing is a complex process based on the coordinated signaling molecules and
dynamic interactions between the engineered scaffold and newly formed tissue. So far, most …
dynamic interactions between the engineered scaffold and newly formed tissue. So far, most …
MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines
Human mesenchymal stem cells (hMSCs) represent promising tools in various clinical
applications, including the regeneration of injured tissues by endogenous or transplanted …
applications, including the regeneration of injured tissues by endogenous or transplanted …
Functional roles of matrix metalloproteinases and their inhibitors in melanoma
S Napoli, C Scuderi, G Gattuso, V Di Bella, S Candido… - Cells, 2020 - mdpi.com
The extracellular matrix (ECM) plays an important role in the regulation of the tissue
microenvironment and in the maintenance of cellular homeostasis. Several proteins with a …
microenvironment and in the maintenance of cellular homeostasis. Several proteins with a …
The role of chalcones in suppression of NF-κB-mediated inflammation and cancer
Although consumption of fruits, vegetables, spices, cereals and pulses has been associated
with lower incidence of cancer and other chronic diseases, how these dietary agents and …
with lower incidence of cancer and other chronic diseases, how these dietary agents and …
Regulation of matrix metalloproteinase activity in health and disease
E Hadler‐Olsen, B Fadnes, I Sylte… - The FEBS …, 2011 - Wiley Online Library
The activity of matrix metalloproteinases (MMPs) is regulated at several levels, including
enzyme activation, inhibition, complex formation and compartmentalization. Regulation at …
enzyme activation, inhibition, complex formation and compartmentalization. Regulation at …
Gelatinase-mediated migration and invasion of cancer cells
M Björklund, E Koivunen - Biochimica et Biophysica Acta (BBA)-Reviews …, 2005 - Elsevier
The matrix metalloproteinases (MMP)-2 and-9, also known as the gelatinases have been
long recognized as major contributors to the proteolytic degradation of extracellular matrix …
long recognized as major contributors to the proteolytic degradation of extracellular matrix …
Hydrogels and dentin–pulp complex regeneration: from the benchtop to clinical translation
Dentin–pulp complex is a term which refers to the dental pulp (DP) surrounded by dentin
along its peripheries. Dentin and dental pulp are highly specialized tissues, which can be …
along its peripheries. Dentin and dental pulp are highly specialized tissues, which can be …
Multifaceted role of matrix metalloproteinases (MMPs)
D Singh, SK Srivastava, TK Chaudhuri… - Frontiers in molecular …, 2015 - frontiersin.org
Matrix metalloproteinases (MMPs), a large family of calcium-dependent zinc-containing
endopeptidases, are involved in the tissue remodeling and degradation of the extracellular …
endopeptidases, are involved in the tissue remodeling and degradation of the extracellular …