Neutrophils are the most abundant of all white blood cells in the human circulation and are
usually associated with inflammation and with fighting infections. In recent years the role …

Since its original identification as a leukocyte gelatinase/type V collagenase and tumour
type IV collagenase, gelatinase B/matrix metalloproteinase (MMP)-9 is now recognised as …

Rationale: Giant cell arteritis (GCA)—a primary vasculitis of medium and large arteries—is
associated with vessel wall damage, elastic membrane fragmentation, and vascular …

Gelatinases (matrix metalloproteinase-2 and-9) are enzymes from the matrix
metalloproteinases (MMPs) family, which are associated with collagen degradation. MMP-2 …

Adhesive procedures activate dentin-associated matrix metalloproteinases (MMPs), and so
iatrogenically initiate bond degradation. We hypothesized that adding MMP inhibitors to …

Human matrix metalloproteinases (MMPs) belong to the M10 family of the MA clan of
endopeptidases. They are ubiquitarian enzymes, structurally characterized by an active site …

Background Skin injury and the resultant defects are common clinical problems, and usually
lead to chronic skin ulcers and even life-threatening diseases. Copper, an essential trace …

It has been postulated that the development of amyloid plaques in Alzheimer's disease (AD)
may result from an imbalance between the generation and clearance of the amyloid-β …

Matrix metalloproteinases (MMPs), originally discovered to function in the breakdown of
extracellular matrix proteins, have gained the status of regulatory proteases in signaling …

The pathological hallmark of Alzheimer disease is the senile plaque principally composed of
tightly aggregated amyloid-β fibrils (fAβ), which are thought to be resistant to degradation …