Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances
SM Hosseini, B Borys, S Karimi-Abdolrezaee - Brain, 2024 - academic.oup.com
Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …
sensory, motor and autonomic impairments after SCI are substantially attributed to …
Incorporating combinatorial approaches to encourage targeted neural stem/progenitor cell integration following transplantation in spinal cord injury
K Pieczonka, MG Fehlings - Stem Cells Translational Medicine, 2023 - academic.oup.com
Spinal cord injury (SCI) severely diminishes quality of life and presents patients with a
substantial financial burden. The lack of a curative treatment has guided efforts toward …
substantial financial burden. The lack of a curative treatment has guided efforts toward …
[HTML][HTML] Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function
In cell transplantation therapy for spinal cord injury (SCI), grafted human induced pluripotent
stem cell-derived neural stem/progenitor cells (hiPSC-NS/PCs) mainly differentiate into …
stem cell-derived neural stem/progenitor cells (hiPSC-NS/PCs) mainly differentiate into …
Rehabilitative Training Enhances Therapeutic Effect of Human iPSC-Derived Neural Stem/Progenitor Cells Transplantation in Chronic Spinal Cord Injury
Cell transplantation therapy using human induced pluripotent stem cell-derived neural
stem/progenitor cells (hiPSC-NS/PCs) is a new therapeutic strategy for spinal cord injury …
stem/progenitor cells (hiPSC-NS/PCs) is a new therapeutic strategy for spinal cord injury …
Treadmill training based on the overload principle promotes locomotor recovery in a mouse model of chronic spinal cord injury
T Shibata, S Tashiro, M Shinozaki, S Hashimoto… - Experimental …, 2021 - Elsevier
Rehabilitative treatment, including treadmill training, is considered an important strategy for
restoring motor function after spinal cord injury (SCI). However, many unexplained problems …
restoring motor function after spinal cord injury (SCI). However, many unexplained problems …
Long-term effects of neural precursor cell transplantation on secondary injury processes and functional recovery after severe cervical contusion-compression spinal …
A Younsi, G Zheng, L Riemann, M Scherer… - International journal of …, 2021 - mdpi.com
Cervical spinal cord injury (SCI) remains a devastating event without adequate treatment
options despite decades of research. In this context, the usefulness of common preclinical …
options despite decades of research. In this context, the usefulness of common preclinical …
Motor learning and physical exercise in adaptive myelination and remyelination
MS Bloom, J Orthmann-Murphy, JB Grinspan - ASN neuro, 2022 - journals.sagepub.com
The idea that myelination is driven by both intrinsic and extrinsic cues has gained much
traction in recent years. Studies have demonstrated that myelination occurs in an intrinsic …
traction in recent years. Studies have demonstrated that myelination occurs in an intrinsic …
Regenerative rehabilitation and stem cell therapy targeting chronic spinal cord injury: a review of preclinical studies
Stem cell medicine has led to functional recovery in the acute-to-subacute phase of spinal
cord injury (SCI), but not yet in the chronic phase, during which various molecular …
cord injury (SCI), but not yet in the chronic phase, during which various molecular …
A review of treatment methods focusing on human induced pluripotent stem cell-derived neural stem/progenitor cell transplantation for chronic spinal cord injury
Cell transplantation therapy using human induced pluripotent stem cell-derived neural
stem/progenitor cells (hiPSC-NS/PCs) has attracted attention as a regenerative therapy for …
stem/progenitor cells (hiPSC-NS/PCs) has attracted attention as a regenerative therapy for …
Exercise combined with administration of adipose-derived stem cells ameliorates neuropathic pain after spinal cord injury
X Cheng, GP Mao, WJ Hu, ZR Yu, YY Xu… - Neural Regeneration …, 2023 - journals.lww.com
Experimental studies have shown that exercise and human adipose-derived stem cells
(ADSCs) play positive roles in spinal cord injury (SCI). However, whether ADSCs and/or …
(ADSCs) play positive roles in spinal cord injury (SCI). However, whether ADSCs and/or …