The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …

Near‐infrared (NIR) activatable fluorescent probes have been considered to be the effective
edge tools for the investigation of cell biology and disease diagnosis because of their …

Chemodynamic therapy (CDT) utilizes Fenton catalysts to convert intracellular hydrogen
peroxide (H 2 O 2) into cytotoxic hydroxyl radical (OH∙) for tumor therapy, but endogenous H …

Hypoxia is a state of low oxygen tension found in numerous solid tumours. It is typically
associated with abnormal vasculature, which results in a reduced supply of oxygen and …

Accurate prediction of the adverse effects of test compounds on living systems, detection of
toxic thresholds, and expansion of experimental data sets to include multiple toxicity end …

Reactive oxygen species (ROS) are important in regulating normal cellular processes, but
deregulated ROS contribute to the development of various human diseases, including …

We show here the identity of Alamar Blue as resazurin. The 'resazurin reduction test'has
been used for about 50 years to monitor bacterial and yeast contamination of milk, and also …

Comparisons of 2D and 3D cell culture models in literature have indicated differences in
cellular morphology and metabolism, commonly attributed the better representation of in …

Lung cancer is the second most common cancer and the leading cause of death in both men
and women in the world. Lung cancer is heterogeneous in nature and diagnosis is often at …

Drug resistance is a major challenge in cancer treatment. The substrates of NAD (P) H:
quinone oxidoreductase 1 (NQO1) show a promising anticancer effect in clinical trials. We …