Bioactive inorganic nanomaterials for cancer theranostics

Z Pei, H Lei, L Cheng - Chemical Society Reviews, 2023 - pubs.rsc.org
Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

Programmed cell death tunes tumor immunity

J Liu, M Hong, Y Li, D Chen, Y Wu, Y Hu - Frontiers in immunology, 2022 - frontiersin.org
The demise of cells in various ways enables the body to clear unwanted cells. Studies over
the years revealed distinctive molecular mechanisms and functional consequences of …

ZIF‐8 nanoparticles evoke pyroptosis for high‐efficiency cancer immunotherapy

B Ding, H Chen, J Tan, Q Meng… - Angewandte Chemie …, 2023 - Wiley Online Library
Although zeolitic imidazolate framework‐8 (ZIF‐8) has been applied in various tumor
therapies, the intrinsic immunogenicity remains unclear. Here, we initiatively discover that …

Biodegradable Ca2+ Nanomodulators Activate Pyroptosis through Mitochondrial Ca2+ Overload for Cancer Immunotherapy

P Zheng, B Ding, G Zhu, C Li, J Lin - Angewandte Chemie, 2022 - Wiley Online Library
Pyroptosis provides a new direction and broad prospects for cancer immunotherapy.
However, the development of a nanoplatform as a pyroptosis inducer is limited, and the …

Copper‐Bacteriochlorin Nanosheet as a Specific Pyroptosis Inducer for Robust Tumor Immunotherapy

Y Zhang, Q Jia, J Li, J Wang, K Liang, X Xue… - Advanced …, 2023 - Wiley Online Library
Pyroptosis is increasingly considered a new weathervane in cancer immune therapy.
However, triggering specific pyroptotic tumor cell death while preserving normal cells still …

State of the art advancements in sonodynamic therapy (SDT): Metal-Organic frameworks for SDT

Z Xiao, Q Chen, Y Yang, S Tu, B Wang, Y Qiu… - Chemical Engineering …, 2022 - Elsevier
Sonodynamic therapy (SDT) is a promising cancer therapy due to its noninvasiveness,
negligible side effects, and deep tissue penetration. However, the effect of SDT is …

Surface modified lanthanide upconversion nanoparticles for drug delivery, cellular uptake mechanism, and current challenges in NIR-driven therapies

AA Ansari, AK Parchur, G Chen - Coordination chemistry reviews, 2022 - Elsevier
Abstract Lanthanides (Ln 3+) are a particular class of optical materials and are regularly
utilized as a structure block for architectures of optoelectronic frameworks because of their …

Recent progress of metal‐based nanomaterials with anti‐tumor biological effects for enhanced cancer therapy

H Lei, Z Pei, C Jiang, L Cheng - Exploration, 2023 - Wiley Online Library
Metal‐based nanomaterials have attracted broad attention recently due to their unique
biological physical and chemical properties after entering tumor cells, namely biological …

Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Emerging pyroptosis-engineered nanobiotechnologies regulate cancers and inflammatory diseases: A double-edged sword

Y Zhang, C Fang, W Zhang, K Zhang - Matter, 2022 - cell.com
Pyroptosis is closely associated with tumors and inflammatory diseases. By enhancing
pyroptosis, direct and immune-response-triggered deaths of tumor cells are increased …