Maternal SARS-CoV-2 infection triggers placental inflammation and alters cord blood
immune cell composition. However, most studies focus on outcomes of severe maternal …

Autophagy is a bulk degradation system that maintains cellular homeostasis by producing
energy and/or recycling excess proteins. During early placentation, extravillous trophoblasts …

A balance between pro-inflammatory decidual CD4+ T cells and FOXP3+ regulatory T cells
(FOXP3+ Tregs) is important for maintaining fetomaternal tolerance. Using single-cell RNA …

Context Elevated body mass index (BMI) in pregnancy is associated with adverse maternal
and fetal outcomes. The placental transcriptome may elucidate molecular mechanisms …

Objective Maternal obesity is increasingly common and negatively impacts offspring health.
Children of mothers with obesity are at higher risk of developing diseases linked to …

Excess maternal adiposity (ie, overweight and obesity) during pregnancy has been linked to
impaired uteroplacental perfusion, compromised placental development, and a higher risk of …

One third of women in the United States are affected by obesity during pregnancy. Maternal
obesity (MO) is associated with an increased risk of neurodevelopmental and metabolic …

Background: Randomized controlled trials have shown that metformin treatment during
pregnancy slows down gestational weight gain (GWG) and reduces the risk of preterm birth …

The obesity epidemic has led to a growing body of research investigating the consequences
of maternal obesity on pregnancy and offspring health. The placenta, traditionally viewed as …