New applications of lipid and polymer-based nanoparticles for nucleic acids delivery

AG Niculescu, AC Bîrcă, AM Grumezescu - Pharmaceutics, 2021 - mdpi.com
Nucleic acids represent a promising lead for engineering the immune system. However,
naked DNA, mRNA, siRNA, and other nucleic acids are prone to enzymatic degradation and …

Phytochemistry, pharmacological investigations, industrial applications, and encapsulation of Thymbra capitata L., a review

C Saoulajan, N Boujida, A El Mihyaoui… - Trends in Food Science …, 2022 - Elsevier
Background Thymbra capitata is a medicinal and aromatic plant of the Lamiaceae family.
Essential oils, organic extracts, and vegetable oils from this species showed a diversity of …

Virtual screening of bioactive anti-SARS-CoV natural products and identification of 3β, 12-diacetoxyabieta-6, 8, 11, 13-tetraene as a potential inhibitor of SARS-CoV-2 …

AKMM Huq, M Roney, S Imran, SU Khan… - Journal of …, 2023 - Taylor & Francis
Since the first prevalence of COVID-19 in 2019, it still remains the most devastating
pandemic throughout the world. The current research aimed to find potential natural …

Antiviral compounds based on natural Astragalus polysaccharides (APS): Research and foresight in the strategies for combating SARS-CoV-2 (COVID-19)

E Aleebrahim-Dehkordi… - Mini Reviews in …, 2022 - ingentaconnect.com
Today, finding natural polymers with desirable properties for use in various industries is one
of the critical axes of research in the world. Polysaccharides are a group of natural polymers …

[HTML][HTML] A review on in silico virtual screening methods in COVID-19 using anticancer drugs and other natural/chemical inhibitors

B Sokouti - Exploration of Targeted Anti-tumor Therapy, 2023 - ncbi.nlm.nih.gov
The present coronavirus disease 2019 (COVID-19) pandemic scenario has posed a difficulty
for cancer treatment. Even under ideal conditions, malignancies like small cell lung cancer …

De Novo Drug Design of Potential Inhibitors of SARS-CoV-2 Papain-like Protease

ECR Lopez - Medical Sciences Forum, 2023 - mdpi.com
Here, potential inhibitors of the SARS-CoV-2 papain-like protease (PLpro) are reported. A
drug molecule (PLpro-50), designed de novo using generative neural networks, interacts …