Biomimetic gland models with engineered stratagems
X Lin, L Sun, M Lu, Y Zhao - Research, 2023 - spj.science.org
As extensively distributed tissues throughout the human body, glands play a critical role in
various physiological processes. Therefore, the construction of biomimetic gland models in …
various physiological processes. Therefore, the construction of biomimetic gland models in …
Defining the challenges and opportunities for using patient‐derived models in prostate cancer research
Background There are relatively few widely used models of prostate cancer compared to
other common malignancies. This impedes translational prostate cancer research because …
other common malignancies. This impedes translational prostate cancer research because …
Patient-derived tumor xenograft study with CDK4/6 inhibitor plus AKT inhibitor for the management of metastatic castration-resistant prostate cancer
AM Kase, J Gleba, JL Miller, E Miller, J Petit… - Molecular Cancer …, 2024 - AACR
Metastatic castration-resistant prostate cancer (mCRPC) is an aggressive malignancy with
poor outcomes. To investigate novel therapeutic strategies, we characterized three new …
poor outcomes. To investigate novel therapeutic strategies, we characterized three new …
Organoid Models Derived from Primary Tumors and Patient-Derive Xenograft Tumors Reflect Platinum Sensitivity of Ovarian Cancer Patients
P Nikeghbal, D Burke, MP Steinkamp - bioRxiv, 2024 - biorxiv.org
Ovarian cancer (OC) remains the deadliest gynecological cancer, primarily due to late stage
diagnosis and high rates of chemotherapy resistance and recurrence. Lack of representative …
diagnosis and high rates of chemotherapy resistance and recurrence. Lack of representative …