A guide to the composition and functions of the extracellular matrix
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …
provides structural support for the cells and tissues. Accumulated knowledge clearly …
Nanostructured particles assembled from natural building blocks for advanced therapies
Advanced treatments based on immune system manipulation, gene transcription and
regulation, specific organ and cell targeting, and/or photon energy conversion have …
regulation, specific organ and cell targeting, and/or photon energy conversion have …
New aspects of vitamin D metabolism and action—Addressing the skin as source and target
D Bikle, S Christakos - Nature Reviews Endocrinology, 2020 - nature.com
Vitamin D has a key role in stimulating calcium absorption from the gut and promoting
skeletal health, as well as many other important physiological functions. Vitamin D is …
skeletal health, as well as many other important physiological functions. Vitamin D is …
[HTML][HTML] CD44: a multifunctional cell surface adhesion receptor is a regulator of progression and metastasis of cancer cells
LT Senbanjo, MA Chellaiah - Frontiers in cell and developmental …, 2017 - frontiersin.org
CD44 is a cell surface adhesion receptor that is highly expressed in many cancers and
regulates metastasis via recruitment of CD44 to the cell surface. Its interaction with …
regulates metastasis via recruitment of CD44 to the cell surface. Its interaction with …
[HTML][HTML] Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage
CL Hawkins, MJ Davies - Free Radical Biology and Medicine, 2021 - Elsevier
The heme peroxidase family generates a battery of oxidants both for synthetic purposes, and
in the innate immune defence against pathogens. Myeloperoxidase (MPO) is the most …
in the innate immune defence against pathogens. Myeloperoxidase (MPO) is the most …
[HTML][HTML] Cancer metastases: challenges and opportunities
X Guan - Acta pharmaceutica sinica B, 2015 - Elsevier
Cancer metastasis is the major cause of cancer morbidity and mortality, and accounts for
about 90% of cancer deaths. Although cancer survival rate has been significantly improved …
about 90% of cancer deaths. Although cancer survival rate has been significantly improved …
[HTML][HTML] Development and application of hyaluronic acid in tumor targeting drug delivery
Z Luo, Y Dai, H Gao - Acta Pharmaceutica Sinica B, 2019 - Elsevier
Hyaluronic acid (HA) is a natural polysaccharide that has gained much attention due to its
biocompatibility, enzyme degradation capacity and active tumor targeting capacity. Its …
biocompatibility, enzyme degradation capacity and active tumor targeting capacity. Its …
[HTML][HTML] Cancer stem cell functions in hepatocellular carcinoma and comprehensive therapeutic strategies
YC Liu, CT Yeh, KH Lin - Cells, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is a significant cause of cancer-related mortality owing to
resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …
resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …
Hyaluronic acid for anticancer drug and nucleic acid delivery
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …
Applications and emerging trends of hyaluronic acid in tissue engineering, as a dermal filler and in osteoarthritis treatment
A Fakhari, C Berkland - Acta biomaterialia, 2013 - Elsevier
Hyaluronic acid (HA) is a naturally occurring biodegradable polymer with a variety of
applications in medicine, including scaffolding for tissue engineering, dermatological fillers …
applications in medicine, including scaffolding for tissue engineering, dermatological fillers …