Chitosan is the most abundant natural biopolymer, after cellulose. It is mainly derived from
the fungi, shrimp's shells, and exoskeleton of crustaceans, through the deacetylation of …

Cancer is an intricate disease that develops as a response to a combination of hereditary
and environmental risk factors, which then result in a variety of changes to the genome. The …

Timely lysosome escape is of paramount importance for endocytosed nanomedicines to
avoid premature degradation under the acidic and hydrolytic conditions in lysosomes …

Ionic liquids (ILs) have huge potential to provide advances in many areas such as energy,
pharmaceutical formulations, biomedical sciences, and technology. In the biomedical field …

Nanoparticles (NPs) are one of the leading and promising technologies for gene and drug
delivery. However, despite continuous advancements in the delivery of NPs, endosomal …

Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and
biodegradable nature of chitosan, it is intensively utilized in biomedical applications in …

Biomaterial scaffolds that support cell infiltration and tissue formation can also function as
platforms for the delivery of therapeutics such as drugs, proteins, and genes. As burst …

Aim: Our goal was to improve treatment outcomes for visceral leishmaniasis by designing
nanocarriers that improve drug biodistribution and half-life. Thus, long-acting mannose …

Polyethylenimine (PEI) is a highly efficient cationic polymer for nucleic acid delivery, and
although it is commonly used in preclinical studies, its clinical application is limited because …

In this work, multifunctional lipid nanocapsules (M-LNC) were designed to combine the
activity of the cytotoxic drug paclitaxel (PTX) with the immunostimulant CpG. This …