6 Tumori Journal 106 (1) study, combining vinorelbine with cyclophosphamide (a drug
known to be active in rhabdomyosarcoma), in an unusual, continuous low-dose oral …

Introduction. The role of vinorelbine in specific soft tissue sarcoma subtypes is unclear. We
present retrospective single institution experience with single‐agent vinorelbine in subjects …

We report two cases of abdominal desmoplastic small round cell tumor (DSRCT) that
showed a clinical response to the vinorelbine/low‐dose cyclophosphamide combination that …

Paediatric sarcomas are a heterogeneous group of disorders constituting bone sarcoma and
various soft tissue sarcomas. Almost one-third of these presents with metastasis at baseline …

Over the past 35 years, cure rates for pediatric cancers have increased dramatically.
However, it is clear that further dose intensification using cytotoxic agents or radiation …

Synovial sarcoma is a soft tissue cancer associated with a recurrent t (X: 18) translocation
that generates one of two fusion proteins, SYT-SSX1 or SYT-SSX2. In this study, we …

Introduction: Metronomic maintenance therapy (MMT) has significantly improved the survival
of patients with high-risk rhabdomyosarcoma in clinical trials. However, there remains a lack …

Introduction: Soft-tissue sarcomas are rare, but they represent about 8% of all malignancies
in pediatric age. Developing a multidisciplinary approach to treatment based on risk …

For the subgroup of patients with inoperable gastrointestinal stromal tumors, progress has
been made by the rapid development and approval of the targeted therapy imatinib …

Childhood malignant gliomas are rare and their clinical behavior is almost as aggressive as
in adults: they resist treatment, progress rapidly and often spread. Therapeutic strategies at …