Testicular tumours in dogs are of Sertoli cell, Leydig cell or germinal origin and mixed
tumours are also frequently observed. The cellular components of mixed tumours are …

Epigenetic modifications characterized by DNA methylation, histone modifications, and
chromatin remodeling are important regulators in a number of biological processes …

Purpose: Cancer-testis genes mapping to the X chromosome have common expression
patterns and show similar responses to modulators of epigenetic mechanisms. We asked …

Although assisted reproductive technology (ART) has become a routine practice for human
infertility treatment, the etiology of the increased risks for perinatal problems in ART …

Complex traits, including those involved in diet-related diseases, are determined by multiple
genes and environmental influences. Factors influencing the development of complex traits …

The production of mature germ cells capable of generating totipotent zygotes is a highly
specialized and sexually dimorphic process. The transition from diploid primordial germ cell …

The advent of in vitro fertilization (IVF) in animals and humans implies an extraordinary
change in the environment where the beginning of a new organism takes place. In mammals …

In contrast to earlier views that there was much compartmentalization of the types of
sequences subject to cancer-linked changes in DNA epigenetics, it is now clear that both …

Stochastic, environmentally and/or genetically induced disturbances in the genome-wide
epigenetic reprogramming processes during male germ-cell development may contribute to …

DNA methylation is one of the epigenetic marks and plays critically important functions
during spermatogenesis in mammals. DNA methylation is catalysed by DNA …