Scale-up of malaria control interventions has resulted in a substantial decline in global
malaria morbidity and mortality. Despite this achievement, there is evidence that current …

Naturally acquired immunity to falciparum malaria protects millions of people routinely
exposed to Plasmodium falciparum infection from severe disease and death. There is no …

Background Transmission intensity affects almost all aspects of malaria epidemiology and
the impact of malaria on human populations. Maps of transmission intensity are necessary to …

Background Over the past decade malaria intervention coverage has been scaled up across
Africa. However, it remains unclear what overall reduction in transmission is achievable …

Mathematical models have been used to provide an explicit framework for understanding
malaria transmission dynamics in human population for over 100 years. With the disease …

Malaria, one of the greatest historical killers of mankind, continues to claim around half a
million lives annually, with almost all deaths occurring in children under the age of five living …

Fundamental gaps remain in our understanding of how immunity to malaria develops. We
used detailed clinical and entomological data from parallel cohort studies conducted across …

Climate change impacts on malaria are typically assessed with scenarios for the long-term
future. Here we focus instead on the recent past (1970–2003) to address whether warmer …

Background Malaria is a major public health issue in much of the world, and the mosquito
vectors which drive transmission are key targets for interventions. Mathematical models for …

As malaria declines in parts of Africa and elsewhere, and as more countries move towards
elimination, it is necessary to robustly evaluate the effect of interventions and control …