The blood–brain barrier is playing a critical role in controlling the influx and efflux of
biological substances essential for the brain's metabolic activity as well as neuronal function …

In recent years there has been a resurgence of interest in brain barriers and various roles
their intrinsic mechanisms may play in neurological disorders. Such studies require suitable …

The existence of the blood-brain barrier (BBB) b was revealed through studies by Ehrlich
(1885) in the late 19th century, describing that brain tissue remained unstained after …

Emotional arousal influences the consolidation of long-term memory. This review discusses
experimental approaches and relevant findings that provide the foundation for current …

Loss of integrity of the blood–brain barrier (BBB) resulting from ischemia/reperfusion is
believed to be a precursor to hemorrhagic transformation (HT) and poor outcome. We used …

Neurological diseases are often associated with cerebrovascular dysfunction and changes
in blood–brain barrier (BBB) function. This is important for two seemingly conflicting reasons …

Purpose: Occurrence of brain damage is frequently associated with abnormal blood-brain
barrier (BBB) function. Two brain-specific proteins, S100β and neuron-specific enolase …

Upon reperfusion of ischemic tissues, reactive oxygen metabolites are generated and are
responsible for much of the organ damage. Experimental studies have revealed two main …

Transient ischemic brain injury causes massive neuronal death in the hippocampus of both
humans and animals. This was accompanied by progressive atrophy of the hippocampus …

Following ischemia, the blood–brain barrier is compromised in the peri-infarct zone leading
to secondary injury and dysfunction that can limit recovery. Currently, it is uncertain what …