Elevated impulsivity is a symptom shared by various psychiatric disorders such as
substance use disorder, bipolar disorder, and attention-deficit/hyperactivity disorder …

The aim of this review is to explore how metabolic changes induced by diets high in
saturated fat (HFD) affect nucleus accumbens (NAc) dopamine neurotransmission and food …

Delineating common and separable neural alterations in substance use disorders (SUD) is
imperative to understand the neurobiological basis of the addictive process and to inform …

Background Animal models of addiction suggest that the transition from incentive-driven
drug use to habitual and ultimately compulsive drug use is mediated by a shift from ventral to …

Behavioral impulsivity is common in various psychiatric and metabolic disorders. Here we
identify a hypothalamus to telencephalon neural pathway for regulating impulsivity involving …

Individuals with mood disorders or with addiction, impulsivity and some personality
disorders can share in common a dysfunction in how the brain perceives reward, where …

The bidirectional selective breeding of Roman high-(RHA) and low-avoidance (RLA) rats for
respectively rapid vs. poor acquisition of active avoidant behavior has generated two …

The risky decision-making task (RDT) measures risk-taking in a rat model by assessing
preference between a small, safe reward and a large reward with increasing risk of …

Impulsive choice, often characterized by excessive preference for small, short-term rewards
over larger, long-term rewards, is a prominent feature of substance use and other …

This brief commentary aims to provide an overview of the available and relatively new
precision management of reward deficiencies manifested as substance and behavioral …