NF-κB in monocytes and macrophages–an inflammatory master regulator in multitalented immune cells

M Mussbacher, M Derler, J Basílio… - Frontiers in …, 2023 - frontiersin.org
Nuclear factor κB (NF-κB) is a dimeric transcription factor constituted by two of five protein
family members. It plays an essential role in inflammation and immunity by regulating the …

Cell type-specific roles of NF-κB linking inflammation and thrombosis

M Mussbacher, M Salzmann, C Brostjan… - Frontiers in …, 2019 - frontiersin.org
The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Biology of interleukin-10

R Sabat, G Grütz, K Warszawska, S Kirsch… - Cytokine & growth factor …, 2010 - Elsevier
Interleukin (IL)-10 is the most important cytokine with anti-inflammatory properties besides
TGF-β and IL-35. It is produced by activated immune cells, in particular monocytes …

The complexity of NF-κB signaling in inflammation and cancer

B Hoesel, JA Schmid - Molecular cancer, 2013 - Springer
The NF-κB family of transcription factors has an essential role in inflammation and innate
immunity. Furthermore, NF-κB is increasingly recognized as a crucial player in many steps of …

[HTML][HTML] Caffeine effects on systemic metabolism, oxidative-inflammatory pathways, and exercise performance

RP Barcelos, FD Lima, NR Carvalho, G Bresciani… - Nutrition Research, 2020 - Elsevier
Caffeine, a xanthine alkaloid compound, is consumed widely and daily by humans, as it is
present in several regular beverages such as tea, coffee, soda beverages, and some drugs …

NF-κB signaling is key in the wound healing processes of silk fibroin

YR Park, MT Sultan, HJ Park, JM Lee, HW Ju, OJ Lee… - Acta biomaterialia, 2018 - Elsevier
Silk fibroin (SF) is a well-studied biomaterial for tissue engineering applications including
wound healing. However, the signaling mechanisms underlying the impact of SF on this …

Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization

H Lu, L Wu, L Liu, Q Ruan, X Zhang, W Hong… - Biochemical …, 2018 - Elsevier
Interstitial inflammation is the main pathological feature in kidneys following injury, and the
polarization of macrophages is involved in the process of inflammatory injury. Previous …

IL-10 family of cytokines

R Sabat - Cytokine & growth factor reviews, 2010 - Elsevier
In 2001, six immune mediators (IL-10, IL-19, IL-20, IL-22, IL-24, and IL-26) were grouped
into the so-called IL-10 family of cytokines based on their similarities with respect to the …

The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING–IFN-β pathway

M Takahashi, CWJ Lio, A Campeau, M Steger… - Nature …, 2021 - nature.com
Evasion of host immunity is a hallmark of cancer; however, mechanisms linking oncogenic
mutations and immune escape are incompletely understood. Through loss-of-function …

Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults

U Raue, TA Trappe, ST Estrem… - Journal of applied …, 2012 - journals.physiology.org
This investigation examined the effects of acute resistance exercise (RE), progressive
resistance training (PRT), and age on the human skeletal muscle Transcriptome. Two …