The pathogenesis of hypoxic—ischemic brain injury in the term infant is multifactorial and
complex. Over the past decade the investigative emphasis has turned to cellular and …

It is well established that glial cells have critical roles in the inflammatory processes in the
central nervous system (CNS). These cells can be activated by a variety of endogenous and …

Periventricular white matter damage (PWMD) also known as periventricular white matter
injury, is one of the major causes of neurological impairment in premature newborns. The …

Nitric oxide (NO) is an important gaseous signaling molecule related to various human
diseases. To investigate the biological functions of NO, many strategies have been …

The delicate balance between the advantageous and detrimental effects of free radicals is
one of the important aspects of human (patho) physiology. The controlled production of …

The experiments were designed to study the glutamate gene expression during epilepsy in
adult and hypoxic insult to brain during the neonatal period and the therapeutic role of …

Hypoxic ischemic encephalopathy (HIE) is a condition that occurs in both human newborns
and foals. The condition is the subject of extensive current research in human infants, but …

Neonatal stroke occurs in approximately 1 in 4,000 to 1 in 10,000 newborns, and more than
80% involve the vascular territory supplied by the middle cerebral artery. Neonatal stroke is …

The NMDA‐type glutamate receptor is a predominant mediator of excitotoxicity in the
immature brain due to overexpression of the receptor in the developing brain. Within the …

Neonatal encephalopathy is a common central nervous system disorder of neonatal foals
and human infants, resulting in clinical signs such as lethargy, inappropriate behavior …