Multiple Factors Determine the Oncolytic or Carcinogenic Effects of TLRs Activation in Cancer
Y Yang, C Jin, A Yeo, B Jin - Journal of Immunology Research, 2024 - Wiley Online Library
Toll‐like receptors (TLRs) belong to a germline‐encoded protein family. These are pattern
recognition receptors. They sense pathogen‐associated molecular patterns (PAMPs). When …
recognition receptors. They sense pathogen‐associated molecular patterns (PAMPs). When …
[HTML][HTML] Identification and analysis of immune-related gene signature in hepatocellular carcinoma
B Shen, G Zhang, Y Liu, J Wang, J Jiang - Genes, 2022 - mdpi.com
Background: Hepatocellular carcinoma (HCC) originates from the hepatocytes and accounts
for 90% of liver cancer. The study intends to identify novel prognostic biomarkers for …
for 90% of liver cancer. The study intends to identify novel prognostic biomarkers for …
[HTML][HTML] Sulforaphane Inhibits IL-1β-Induced IL-6 by Suppressing ROS Production, AP-1, and STAT3 in Colorectal Cancer HT-29 Cells
DK Sah, A Arjunan, SY Park, B Lee, YD Jung - Antioxidants, 2024 - mdpi.com
Colorectal cancer (CRC) stands as a major cause of cancer-related mortality globally,
accounting for approximately 881,000 deaths each year. Traditional approaches such as …
accounting for approximately 881,000 deaths each year. Traditional approaches such as …
Organoids at the PUB: the porcine urinary bladder serves as a pancreatic niche for advanced cancer modeling
Despite intensive research and progress in personalized medicine, pancreatic ductal
adenocarcinoma remains one of the deadliest cancer entities. Pancreatic duct‐like …
adenocarcinoma remains one of the deadliest cancer entities. Pancreatic duct‐like …
[HTML][HTML] Advances in tumor microenvironment and underlying molecular mechanisms of bladder cancer: a systematic review
L Tang, H Xu, T Wu, W Wu, Y Lu, J Gu, X Wang… - Discover Oncology, 2024 - Springer
Bladder cancer is one of the most frequent malignant tumors of the urinary system. The
prevalence of bladder cancer among men and women is roughly 5: 2, and both its incidence …
prevalence of bladder cancer among men and women is roughly 5: 2, and both its incidence …
[HTML][HTML] Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood
Background: Accurate diagnosis of latent tuberculosis infected (LTBI) individuals is
important in identifying individuals at risk of developing active tuberculosis. Current …
important in identifying individuals at risk of developing active tuberculosis. Current …
PBAC: A pathway‐based attention convolution neural network for predicting clinical drug treatment responses
D Deng, X Xu, T Cui, M Xu, K Luo… - Journal of Cellular …, 2024 - Wiley Online Library
Precise and personalized drug application is crucial in the clinical treatment of complex
diseases. Although neural networks offer a new approach to improving drug strategies, their …
diseases. Although neural networks offer a new approach to improving drug strategies, their …
[HTML][HTML] Interleukin-1β/Interleukin (IL)-1-Receptor-Antagonist (IL1-RA) Axis in Invasive Bladder Cancer—An Exploratory Analysis of Clinical and Tumor Biological …
M Vukovic, JM Chamlati, J Hennenlotter… - International Journal of …, 2024 - mdpi.com
Previous data indicate a role of IL-1 and IL-1RA imbalance in bladder carcinoma (BC); the
inhibition of IL-1 signaling might be considered a treatment option. Objective: To assess …
inhibition of IL-1 signaling might be considered a treatment option. Objective: To assess …
青蒿素通过TIGIT/CD155 信号轴调控4T1 乳腺癌细胞转移与凋亡.
冯亚婵, 张皓杰, 杜朝, 郭学玲… - Chinese Journal of …, 2024 - search.ebscohost.com
摘要乳腺癌是严重影响女性生命健康的恶性肿瘤之一. 近年来, 中药植物活性成分⁃ 青蒿素(ar⁃
temisinin, ART) 的抗肿瘤作用愈显突出. 然而, 目前仍不清楚ART 在治疗乳腺癌转移方面的效果 …
temisinin, ART) 的抗肿瘤作用愈显突出. 然而, 目前仍不清楚ART 在治疗乳腺癌转移方面的效果 …
Association of IL-4 and IL-1 Ra Gene Polymorphisms with the Risk of Bladder Cancer
The aim of this study is to evaluate the association of interleukin-4 (IL-4) gene intron 3 and
interleukin-1 receptor antagonist (IL-1Ra) gene intron 2 variable number tandem repeat …
interleukin-1 receptor antagonist (IL-1Ra) gene intron 2 variable number tandem repeat …