Focusing on fibrosis: halofuginone-induced functional improvement in the mdx mouse model of Duchenne muscular dystrophy

LK McLoon - American Journal of Physiology-Heart and …, 2008 - journals.physiology.org
DUCHENNE MUSCULAR DYSTROPHY (DMD) is a devastating X-linked disease caused by
mutations in the gene encoding for dystrophin and characterized by widespread muscle …

阻断Th17 细胞分化对小鼠肠道急性移植物抗宿主病的影响

李护君, 程海, 潘彬, 曾令宇, 徐开林 - 中华血液学杂志, 2012 - cqvip.com
目的观察阻断Th17 细胞分化对小鼠小肠急性移植物抗宿主病(aGVHD) 的影响.
方法将小鼠分为5 组: 正常对照组, 单纯照射组, 异基因骨髓移植(allo—BMT) 组, allo—BMT+ …

Liquid chromatography-electrospray tandem mass spectrometric assay suitable for quantitation of halofuginone in plasma

RA Parise, BR Sparrow, JW Merrill, IM Grossi… - … of Chromatography B, 2004 - Elsevier
An LC-MS/MS method was developed to quantitate the potential antitumor agent
halofuginone in plasma. The assay uses 0.2 ml of plasma; chlorohalofuginone internal …

[PDF][PDF] Pharmacokinetic characterization and therapeutic efficacy of halofuginone micelle nanoparticles in murine models of Nrf2 activated lung adenocarcinoma

P HARIT - tohoku.repo.nii.ac.jp
Abstract The Keap1-Nrf2 system is the master regulator of the cellular response against
oxidative and xenobiotic stresses. Constitutive activation of Nrf2 is frequently observed in …

[PDF][PDF] Halofuginone for adult patients with SARS-Cov-2: Multicentre, phase 2, randomized, double-blind, placebo-controlled clinical trial. HALOfuginone for SARS …

BM Tomazini, FG Zampieri, I Maia, AB Cavalcanti… - scienceopen.com
Halofuginone for adult patients with SARS-Cov-2: Multicentre, phase 2, randomized, double-blind,
placebo-controlled clinical tri Page 1 Halofuginone for adult patients with SARS-Cov-2 …

Halofuginonun deneysel kolon kanserinde etkinliğinin belirlenmesi

O Çorum - 2016 - acikerisim.selcuk.edu.tr
Özet Kolon kanseri dünyada en fazla mortalite ve morbiditeye neden olan kanserlerden
birisidir. Kolon kanseri tedavisinde cerrahi ve medikal tedavinin yanısıra alternatif tedavi …

Stroma-targeting therapies and local intervention in pancreatic ductal adenocarcinoma

KY Elahi-Gedwillo - 2018 - search.proquest.com
Pancreatic ductal adenocarcinoma (PDA) remains one of the deadliest forms of cancer, in
part, because it is largely refractory to current therapies. The failure of most standard …

Linda K McLoon

LK McLoon - 2008 - journals.physiology.org
Duchenne muscular dystrophy (DMD) is a devastating X-linked disease caused by
mutations in the gene encoding for dystrophin and characterized by widespread muscle …

[PDF][PDF] Charakterisierung von 3 Tiermodellen zur Erzeugung einer interstitiellen Fibrose der Rattenniere und therapeutische Beeinflussung der uranylnitratbedingten …

S Sawall - 2003 - d-nb.info
In der vorliegenden Arbeit werden drei verschiedene Tiermodelle zur Erzeugung einer
interstitiellen Nierenfibrose bei erwachsenen weiblichen Wistarratten verglichen: 1. die …

An Innovative Strategy for the Prevention and Treatment of Metastatic Prostate Cancer: Modified Tetracyclines as Chemotherapeutics

B Lokeshwar, MIAMI UNIV FL - 2002 - apps.dtic.mil
In this second year months 12-24 of the Phase II of the project, the molecular basis of
chemoresistance in prostate tumor cells, acquired due to their interaction with stromal cells …