[HTML][HTML] Reduced erythrocyte membrane polyunsaturated fatty acid levels indicate diminished treatment response in patients with multi-versus first-episode …
Antipsychotic effects seem to decrease in relapsed schizophrenia patients and the
underlying mechanisms remain to be elucidated. Based on the essential role of …
underlying mechanisms remain to be elucidated. Based on the essential role of …
[HTML][HTML] Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank
Major depressive disorder (MDD), schizophrenia (SCZ) and bipolar disorder (BP) are
common, disabling and heritable psychiatric diseases with a complex overlapping polygenic …
common, disabling and heritable psychiatric diseases with a complex overlapping polygenic …
Efficacy of adjunctive infliximab vs. placebo in the treatment of anhedonia in bipolar I/II depression
Y Lee, RB Mansur, E Brietzke, NE Carmona… - Brain, behavior, and …, 2020 - Elsevier
We investigated the efficacy of tumour necrosis factor (TNF)-α antagonist infliximab on a
measure of anhedonia amongst individuals with bipolar I/II depression (ClinicalTrials. gov …
measure of anhedonia amongst individuals with bipolar I/II depression (ClinicalTrials. gov …
Brain eicosapentaenoic acid metabolism as a lead for novel therapeutics in major depression
The results of several meta-analyses suggest that eicosapentaenoic acid (EPA)
supplementation is therapeutic in managing the symptoms of major depression. It was …
supplementation is therapeutic in managing the symptoms of major depression. It was …
[HTML][HTML] Brain kynurenine and BH4 pathways: relevance to the pathophysiology and treatment of inflammation-driven depressive symptoms
S Vancassel, L Capuron, N Castanon - Frontiers in Neuroscience, 2018 - frontiersin.org
The prevalence of depressive disorders is growing worldwide, notably due to stagnation in
the development of drugs with greater antidepressant efficacy, the continuous large …
the development of drugs with greater antidepressant efficacy, the continuous large …
On the transdiagnostic nature of peripheral biomarkers in major psychiatric disorders: a systematic review
The search for biomarkers has been a leading endeavor in biological psychiatry. To analyze
its evolution over the years, we performed a systematic review to evaluate (a) the most …
its evolution over the years, we performed a systematic review to evaluate (a) the most …
[HTML][HTML] Effects of n-3 polyunsaturated fatty acid supplementation in the prevention and treatment of depressive disorders—a systematic review and meta-analysis
M Wolters, A von der Haar, AK Baalmann, M Wellbrock… - Nutrients, 2021 - mdpi.com
N-3 polyunsaturated fatty acids (PUFAs) have been suggested to affect depressive
disorders. This review aims to determine the effect of n-3 PUFAs on depressive symptoms in …
disorders. This review aims to determine the effect of n-3 PUFAs on depressive symptoms in …
[HTML][HTML] Long chain omega-3 polyunsaturated fatty acid supplementation alleviates doxorubicin-induced depressive-like behaviors and neurotoxicity in rats …
YQ Wu, RL Dang, MM Tang, HL Cai, HD Li, DH Liao… - Nutrients, 2016 - mdpi.com
Doxorubicin (DOX) is a chemotherapeutic agent widely used in human malignancies. Its
long-term use can cause neurobiological side-effects associated with depression. Omega-3 …
long-term use can cause neurobiological side-effects associated with depression. Omega-3 …
[HTML][HTML] Nutritional neuroscience as mainstream of psychiatry: the evidence-based treatment guidelines for using omega-3 fatty acids as a new treatment for …
Omega-3 polyunsaturated fatty acids (or omega-3 PUFAs, n-3 PUFAs) are essential
nutrients throughout the life span. Recent studies have shown the importance of n-3 PUFAs …
nutrients throughout the life span. Recent studies have shown the importance of n-3 PUFAs …
Cognitive dysfunction in major depression: From assessment to novel therapies
H Atique-Ur-Rehman, JC Neill - Pharmacology & therapeutics, 2019 - Elsevier
Major depressive disorder (MDD) is a disabling disease associated with profound functional
impairment. Cognitive deficits, increasingly recognised as a core feature of MDD, reduce …
impairment. Cognitive deficits, increasingly recognised as a core feature of MDD, reduce …