[HTML][HTML] The controversial role of homocysteine in neurology: from labs to clinical practice

R Moretti, P Caruso - International journal of molecular sciences, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …

[HTML][HTML] Potential biomarkers for post-stroke cognitive impairment: a systematic review and meta-analysis

KY Kim, KY Shin, KA Chang - International journal of molecular sciences, 2022 - mdpi.com
Stroke is a primary debilitating disease in adults, occurring in 15 million individuals each
year and causing high mortality and disability rates. The latest estimate revealed that stroke …

Proteomics in aging research: A roadmap to clinical, translational research

R Moaddel, C Ubaida‐Mohien, T Tanaka… - Aging …, 2021 - Wiley Online Library
The identification of plasma proteins that systematically change with age and, independent
of chronological age, predict accelerated decline of health is an expanding area of research …

[HTML][HTML] Chronic cerebral hypoperfusion: a critical feature in unravelling the etiology of vascular cognitive impairment

V Rajeev, YL Chai, L Poh, S Selvaraji, DY Fann… - Acta neuropathologica …, 2023 - Springer
Vascular cognitive impairment (VCI) describes a wide spectrum of cognitive deficits related
to cerebrovascular diseases. Although the loss of blood flow to cortical regions critically …

[HTML][HTML] Parkinson's disease risk and hyperhomocysteinemia: the possible link

HM Al-Kuraishy, AI Al-Gareeb, YHA Elewa… - Cellular and Molecular …, 2023 - Springer
Parkinson's disease (PD) is one of the most common degenerative brain disorders caused
by the loss of dopaminergic neurons in the substantia nigra (SN). Lewy bodies and …

[HTML][HTML] The role of vitamins in neurodegenerative disease: An update

SN Rai, P Singh, HWM Steinbusch, E Vamanu… - Biomedicines, 2021 - mdpi.com
Acquiring the recommended daily allowance of vitamins is crucial for maintaining
homeostatic balance in humans and other animals. A deficiency in or dysregulation of …

Protein S-sulfhydration: unraveling the prospective of hydrogen sulfide in the brain, vasculature and neurological manifestations

R Gupta, M Sahu, R Tripathi, RK Ambasta… - Ageing Research …, 2022 - Elsevier
Hydrogen sulfide (H 2 S) and hydrogen polysulfides (H 2 S n) are essential regulatory
signaling molecules generated by the entire body, including the central nervous system …

[HTML][HTML] Homocysteine in neurology: a possible contributing factor to small vessel disease

R Moretti, M Giuffre, P Caruso, S Gazzin… - International Journal of …, 2021 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid generated during methionine
metabolism, accumulation of which may be caused by genetic defects or the deficit of …

Chronic alcohol metabolism results in DNA repair infidelity and cell cycle‐induced senescence in neurons

JKL Sun, D Wu, GCN Wong, TM Lau, M Yang… - Aging cell, 2023 - Wiley Online Library
Chronic binge‐like drinking is a risk factor for age‐related dementia, however, the lasting
and irreversible effect of alcohol on the brain remains elusive. Transcriptomic changes in …

[图书][B] Neurodegeneration: Diagnosis, prevention, and therapy

MK Poddar, A Chakraborty, S Banerjee - 2021 - books.google.com
Neurodegenerative disorders (NDDs) are a broad range of pathological conditions which
target the neurons, creating problems in movements and mental functions. The NDDs have …