Polypharmacy management in older patients
RW Hoel, RMG Connolly, PY Takahashi - Mayo Clinic Proceedings, 2021 - Elsevier
Medications to treat disease and extend life in our patients often amass in quantities,
resulting in what has been termed “polypharmacy.” This imprecise label usually describes …
resulting in what has been termed “polypharmacy.” This imprecise label usually describes …
Deprescribing in the older patient: a narrative review of challenges and solutions
H Wu, L Kouladjian O'Donnell, K Fujita… - … journal of general …, 2021 - Taylor & Francis
Polypharmacy is a major challenge in healthcare for older people, and is associated with
increased risks of adverse outcomes, such as delirium, falls, frailty, cognitive impairment and …
increased risks of adverse outcomes, such as delirium, falls, frailty, cognitive impairment and …
Barriers and enablers for deprescribing benzodiazepine receptor agonists in older adults: a systematic review of qualitative and quantitative studies using the …
P Evrard, C Pétein, JB Beuscart, A Spinewine - Implementation Science, 2022 - Springer
Background Many strategies aimed at deprescribing benzodiazepine receptor agonists
(BZRA) in older adults have already been evaluated with various success rates. There is so …
(BZRA) in older adults have already been evaluated with various success rates. There is so …
Deprescribing benzodiazepines in older patients: impact of interventions targeting physicians, pharmacists, and patients
BJ Ng, DG Le Couteur, SN Hilmer - Drugs & aging, 2018 - Springer
Benzodiazepines (BZDs; including the related Z-drugs) are frequently targets for
deprescribing; long-term use in older people is harmful and often not beneficial. BZDs can …
deprescribing; long-term use in older people is harmful and often not beneficial. BZDs can …
A systems approach to identifying the challenges of implementing deprescribing in older adults across different health-care settings and countries: a narrative review
Introduction: There is increasing recognition of the need for deprescribing of inappropriate
medications in older adults. However, efforts to encourage implementation of deprescribing …
medications in older adults. However, efforts to encourage implementation of deprescribing …
Therapeutic dilemmas with benzodiazepines and Z-drugs: insomnia and anxiety disorders versus increased fall risk: a clinical review
A Capiau, L Huys, E van Poelgeest… - European geriatric …, 2023 - Springer
Purpose The aim of this clinical review was to summarise the existing knowledge on fall risk
associated with benzodiazepines (BZDs) and Z-drugs in older people with focus on …
associated with benzodiazepines (BZDs) and Z-drugs in older people with focus on …
Feasibility and effectiveness of deprescribing benzodiazepines and Z‐drugs: systematic review and meta‐analysis
A Soni, A Thiyagarajan, J Reeve - Addiction, 2023 - Wiley Online Library
Background and Aims A total of 2.4 million adults in England were dispensed a
benzodiazepine or Z‐drug (BZRA) in 2017/18, and more than 250 000 patients in the UK …
benzodiazepine or Z‐drug (BZRA) in 2017/18, and more than 250 000 patients in the UK …
Approaches to deprescribing psychotropic medications for changed behaviours in long-term care residents living with dementia
Psychotropic medications have a high risk of serious adverse events and small effect size for
changed behaviours for people with dementia. Non-pharmacological approaches are …
changed behaviours for people with dementia. Non-pharmacological approaches are …
A narrative review of the safety concerns of deprescribing in older adults and strategies to mitigate potential harms
Introduction: As with prescribing or continuing medications, deprescribing brings with it the
potential for harm as well as benefit. Uncertainty and avoidance of harm has been reported …
potential for harm as well as benefit. Uncertainty and avoidance of harm has been reported …
Implementation considerations of deprescribing interventions: a scoping review
Over half of older adults experience polypharmacy, including medications that may be
inappropriate or unnecessary. Deprescribing, which is the process of discontinuing or …
inappropriate or unnecessary. Deprescribing, which is the process of discontinuing or …