Medications to treat disease and extend life in our patients often amass in quantities,
resulting in what has been termed “polypharmacy.” This imprecise label usually describes …

Polypharmacy is a major challenge in healthcare for older people, and is associated with
increased risks of adverse outcomes, such as delirium, falls, frailty, cognitive impairment and …

Background Many strategies aimed at deprescribing benzodiazepine receptor agonists
(BZRA) in older adults have already been evaluated with various success rates. There is so …

Benzodiazepines (BZDs; including the related Z-drugs) are frequently targets for
deprescribing; long-term use in older people is harmful and often not beneficial. BZDs can …

Introduction: There is increasing recognition of the need for deprescribing of inappropriate
medications in older adults. However, efforts to encourage implementation of deprescribing …

Purpose The aim of this clinical review was to summarise the existing knowledge on fall risk
associated with benzodiazepines (BZDs) and Z-drugs in older people with focus on …

Background and Aims A total of 2.4 million adults in England were dispensed a
benzodiazepine or Z‐drug (BZRA) in 2017/18, and more than 250 000 patients in the UK …

Psychotropic medications have a high risk of serious adverse events and small effect size for
changed behaviours for people with dementia. Non-pharmacological approaches are …

Introduction: As with prescribing or continuing medications, deprescribing brings with it the
potential for harm as well as benefit. Uncertainty and avoidance of harm has been reported …

Over half of older adults experience polypharmacy, including medications that may be
inappropriate or unnecessary. Deprescribing, which is the process of discontinuing or …