Plasmids, a molecular cornerstone of antimicrobial resistance in the One Health era

S Castañeda-Barba, EM Top, T Stalder - Nature Reviews Microbiology, 2024 - nature.com
Antimicrobial resistance (AMR) poses a substantial threat to human health. The widespread
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …

Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance

SW Dickey, GYC Cheung, M Otto - Nature Reviews Drug Discovery, 2017 - nature.com
The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens
are outpacing the development of new antibiotics, but antivirulence agents provide an …

Dissemination of antimicrobial resistance in microbial ecosystems through horizontal gene transfer

CJH Von Wintersdorff, J Penders… - Frontiers in …, 2016 - frontiersin.org
The emergence and spread of antibiotic resistance among pathogenic bacteria has been a
rising problem for public health in recent decades. It is becoming increasingly recognized …

[HTML][HTML] Antibiotic resistance: What is so special about multidrug-resistant Gram-negative bacteria?

M Exner, S Bhattacharya, B Christiansen… - GMS hygiene and …, 2017 - ncbi.nlm.nih.gov
In the past years infections caused by multidrug-resistant Gram-negative bacteria have
dramatically increased in all parts of the world. This consensus paper is based on …

Multidrug-resistant bacteria in the community: trends and lessons learned

D Van Duin, DL Paterson - Infectious disease clinics, 2016 - id.theclinics.com
Multidrug resistant (MDR) bacteria are well-recognized to be one of the most important
current public health problems. The Infectious Diseases Society of America recognizes …

Interconnected microbiomes and resistomes in low-income human habitats

EC Pehrsson, P Tsukayama, S Patel, M Mejía-Bautista… - Nature, 2016 - nature.com
Antibiotic-resistant infections annually claim hundreds of thousands of lives worldwide. This
problem is exacerbated by exchange of resistance genes between pathogens and benign …

Antimicrobial resistance on farms: a review including biosecurity and the potential role of disinfectants in resistance selection

R Davies, A Wales - … reviews in food science and food safety, 2019 - Wiley Online Library
Resistance to therapeutic antimicrobial agents is recognized as a growing problem for both
human and veterinary medicine, and the need to address the issue in both of these linked …

Tackling threats and future problems of multidrug-resistant bacteria

E Medina, DH Pieper - How to overcome the antibiotic crisis: facts …, 2016 - Springer
With the advent of the antibiotic era, the overuse and inappropriate consumption and
application of antibiotics have driven the rapid emergence of multidrug-resistant pathogens …

Synergy and Order Effects of Antibiotics and Phages in Killing Pseudomonas aeruginosa Biofilms

WN Chaudhry, J Concepcion-Acevedo, T Park… - PloS one, 2017 - journals.plos.org
In contrast to planktonic cells, bacteria imbedded biofilms are notoriously refractory to
treatment by antibiotics or bacteriophage (phage) used alone. Given that the mechanisms of …

Antibiotic resistance in plant-pathogenic bacteria

GW Sundin, N Wang - Annual Review of phytopathology, 2018 - annualreviews.org
Antibiotics have been used for the management of relatively few bacterial plant diseases
and are largely restricted to high-value fruit crops because of the expense involved …