[HTML][HTML] Strategies for prevention and management of ocular events occurring with mirvetuximab soravtansine
A Hendershot, M Slabaugh, KM Riaz, KN Moore… - Gynecologic Oncology …, 2023 - Elsevier
Mirvetuximab soravtansine (MIRV) is a first-in-class antibody-drug conjugate (ADC)
targeting folate receptor alpha (FRα) and is indicated for the treatment of adult patients with …
targeting folate receptor alpha (FRα) and is indicated for the treatment of adult patients with …
[HTML][HTML] Dupilumab-Induced, Tralokinumab-Induced, and Belantamab Mafodotin–Induced Adverse Ocular Events—Incidence, Etiology, and Management
T Mickevicius, AE Pink, M Bhogal, D O'Brart, SJ Robbie - Cornea, 2023 - journals.lww.com
Emerging monoclonal antibody therapies are assuming greater importance in the
management of severe and refractory forms of immunity-driven and oncological disorders …
management of severe and refractory forms of immunity-driven and oncological disorders …
[HTML][HTML] Corneal in vivo confocal microscopy to detect belantamab mafodotin-induced ocular toxicity early and adjust the dose accordingly: a case report
K Marquant, A Quinquenel, C Arndt… - Journal of Hematology & …, 2021 - Springer
Background New targeted antibody–drug conjugates (ADCs) against multiple myeloma are
known to induce adverse effects that may lead to treatment discontinuation. Preclinical …
known to induce adverse effects that may lead to treatment discontinuation. Preclinical …
Corneal Epithelial Thickness Mapping: A Major Review
MA Abtahi, AH Beheshtnejad, G Latifi… - Journal of …, 2024 - Wiley Online Library
The corneal epithelium (CE) is the outermost layer of the cornea with constant turnover,
relative stability, remarkable plasticity, and compensatory properties to mask alterations in …
relative stability, remarkable plasticity, and compensatory properties to mask alterations in …
Antibody-Drug Conjugates and Ocular Toxicity
M Jaffry, H Choudhry, OM Aftab… - Journal of Ocular …, 2023 - liebertpub.com
Antibody-drug conjugates (ADCs) are a growing class of chemotherapeutic agents for the
purpose of treating cancers that often have relapsed or failed first-and second-line …
purpose of treating cancers that often have relapsed or failed first-and second-line …
[HTML][HTML] Incidence and mitigation of corneal pseudomicrocysts induced by antibody–drug conjugates (ADCs)
Abstract Purpose of Review This study is to highlight the incidence of corneal
pseudomicrocysts in FDA-approved antibody–drug conjugates (ADCs), and success of …
pseudomicrocysts in FDA-approved antibody–drug conjugates (ADCs), and success of …
[HTML][HTML] Corneal findings associated to belantamab-mafodotin (belamaf) use in a series of patients examined longitudinally by means of advanced corneal imaging
R Mencucci, M Cennamo, L Alonzo, C Senni… - Journal of clinical …, 2022 - mdpi.com
Belantamab mafodotin (belamaf) is a novel antibody–drug conjugate developed for the
treatment of patients with relapsed or refractory multiple myeloma (RRMM). Although the …
treatment of patients with relapsed or refractory multiple myeloma (RRMM). Although the …
A safety review of recently approved and emerging drugs for patients with relapsed or refractory multiple myeloma
S Midha, MA Hartley-Brown, CC Mo… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Multiple new drugs have been approved over the past 5 years for the treatment
of relapsed/refractory multiple myeloma (RRMM), and these are being increasingly widely …
of relapsed/refractory multiple myeloma (RRMM), and these are being increasingly widely …
[HTML][HTML] Semi-automation of keratopathy visual acuity grading of corneal events in belantamab mafodotin clinical trials: clinical decision support software
MK Talekar, JL Painter, MA Elizalde… - Frontiers in Digital …, 2023 - frontiersin.org
Background: Belantamab mafodotin (belamaf) has demonstrated clinically meaningful
antimyeloma activity in patients with heavily pretreated multiple myeloma. However, it is …
antimyeloma activity in patients with heavily pretreated multiple myeloma. However, it is …
Corneal Epithelial Thickness Mapping: A Major Review
A Mohammad-Ali, AH Beheshtnejad… - Journal of …, 2024 - search.proquest.com
The corneal epithelium (CE) is the outermost layer of the cornea with constant turnover,
relative stability, remarkable plasticity, and compensatory properties to mask alterations in …
relative stability, remarkable plasticity, and compensatory properties to mask alterations in …