Applications and limitations of dendrimers in biomedicine

AA Chis, C Dobrea, C Morgovan, AM Arseniu, LL Rus… - Molecules, 2020 - mdpi.com
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …

Novel drug delivery systems for loading of natural plant extracts and their biomedical applications

HS Rahman, HH Othman, NI Hammadi… - International journal …, 2020 - Taylor & Francis
Many types of research have distinctly addressed the efficacy of natural plant metabolites
used for human consumption both in cell culture and preclinical animal model systems …

Dendrimers: amazing platforms for bioactive molecule delivery systems

C Sandoval-Yañez, C Castro Rodriguez - Materials, 2020 - mdpi.com
Today, dendrimers are the main nanoparticle applied to drug delivery systems. The
physicochemical characteristics of dendrimers and their versatility structural modification …

A glance over doxorubicin based-nanotherapeutics: From proof-of-concept studies to solutions in the market

M Gonçalves, S Mignani, J Rodrigues… - Journal of Controlled …, 2020 - Elsevier
Cancer is one of the leading causes of death worldwide and, as such, efforts are being done
to find new chemotherapeutic drugs or, alternatively, novel approaches for the delivery of old …

Functionalized PAMAM constructed nanosystems for biomacromolecule delivery

KH Wong, Z Guo, MK Law, M Chen - Biomaterials Science, 2023 - pubs.rsc.org
Polyamidoamines (PAMAMs) are a class of dendrimer with monodispersity and controlled
topology, which can deliver biologically active macromolecules (eg, genes and proteins) to …

A review on poly (amidoamine) dendrimer encapsulated nanoparticles synthesis and usage in energy conversion and storage applications

B Devadas, AP Periasamy, K Bouzek - Coordination Chemistry Reviews, 2021 - Elsevier
The direction of this review is concentrating on the development of poly
(amidoamine)(PAMAM) dendrimer encapsulated metal nanoparticles (NPs), so-called Dend …

In situ synthesis of dendrimer-encapsulated palladium (0) nanoparticles as catalysts for hydrogen production from the methanolysis of ammonia borane

P Eghbali, MU Gürbüz, AS Ertürk, Ö Metin - International Journal of …, 2020 - Elsevier
Addressed herein is the in situ synthesis of a PAMAM dendrimer-encapsulated palladium (0)
NPs (Pd (0)/Dnd) during the methanolysis of ammonia borane (AB) and the catalytic …

Administration routes for nano drugs and characterization of nano drug loading

V Nikolić, S Ilić-Stojanović, S Petrović, A Tačić… - … and biology of …, 2019 - Elsevier
This chapter summarizes the types of nano drugs, their synthesis, formulation,
characterization, and applications, with the most important administration routes. To achieve …

Polyamidoamine dendrimers for enhanced solubility of small molecules and other desirable properties for site specific delivery: Insights from experimental and …

DM Shadrack, HS Swai, JJE Munissi, EB Mubofu… - Molecules, 2018 - mdpi.com
Clinical applications of many small molecules are limited due to poor solubility and lack of
controlled release besides lack of other desirable properties. Experimental and …

Cytotoxicity and in vivo plasma kinetic behavior of surface-functionalized PAMAM dendrimers

C Diaz, C Benitez, F Vidal, LF Barraza… - … , Biology and Medicine, 2018 - Elsevier
Understanding the molecular features responsible for the plasma kinetics of surface-
modified polyamido amine (PAMAM) dendrimers is critical to explore novel biomedical …