Needle-free vaccine delivery

G Kersten, H Hirschberg - Expert opinion on drug delivery, 2007 - Taylor & Francis
The need for minimally invasive delivery methods is urgent. As the number of registered
vaccines increases, so does the number of injections. The use of sharps can be unsafe and …

Induction of broad immunity against invasive salmonella disease by a quadrivalent combination salmonella MAPS vaccine targeting Salmonella Enterica serovars …

EM Boerth, J Gong, B Roffler, CM Thompson, B Song… - Vaccines, 2023 - mdpi.com
Bloodstream infections in low-and middle-income countries (LMICs) are most frequently
attributed to invasive Salmonella disease caused by four primary serovars of Salmonella …

Functional analysis of Salmonella Typhi adaptation to survival in water

RA Kingsley, G Langridge, SE Smith… - Environmental …, 2018 - Wiley Online Library
Contaminated water is a major risk factor associated with the transmission of Salmonella
enterica serovar Typhi (S. Typhi), the aetiological agent of human typhoid. However, little is …

A genetically engineered derivative of Salmonella Enteritidis as a novel live vaccine candidate for salmonellosis in chickens

RM Nandre, K Matsuda, AA Chaudhari, B Kim… - Research in veterinary …, 2012 - Elsevier
To construct a novel live Salmonella Enteritidis (SE) vaccine candidate, SE was genetically
engineered using the allelic exchange method to delete two virulence genes, lon and cpxR …

Induction of Immune Responses in Mice after Oral Immunization with Recombinant Lactobacillus casei Strains Expressing Enterotoxigenic Escherichia coli F41 …

JK Liu, XL Hou, CH Wei, LY Yu, XJ He… - Applied and …, 2009 - Am Soc Microbiol
In an effort to develop a safe and effective vaccine for the prevention of enterotoxigenic
Escherichia coli (ETEC) F41 infections, we have developed a surface antigen display …

Genetic engineering of Salmonella spp. for novel vaccine strategies and therapeutics

G Bansal, M Ghanem, KT Sears, JE Galen… - EcoSal …, 2024 - journals.asm.org
Salmonella enterica is a diverse species that infects both humans and animals. S. enterica
subspecies enterica consists of more than 1,500 serovars. Unlike typhoidal Salmonella …

Evaluation of Salmonella enterica Serovar Typhimurium TTSS-2 Deficient fur Mutant as Safe Live-Attenuated Vaccine Candidate for Immunocompromised Mice

V Vishwakarma, NB Pati, HS Chandel, SS Sahoo… - PLoS …, 2012 - journals.plos.org
Salmonella enterica serovar Typhimurium has been extensively exploited as live attenuated
vaccines (LAV) which generally confers better protection than killed or subunit vaccines …

Enhancement of Immune Responses by an Attenuated Salmonella enterica Serovar Typhimurium Strain Secreting an Escherichia coli Heat-Labile Enterotoxin B Subunit …

J Hur, JH Lee - Clinical and Vaccine Immunology, 2011 - Am Soc Microbiol
ABSTRACT A plasmid harboring eltB, the gene encoding heat-labile enterotoxin (LTB), was
constructed by insertion of eltB into an Asd+ β-lactamase signal plasmid (pMMP65). This …

Trichinella spiralis: intranasal immunization with attenuated Salmonella enterica carrying a gp43 antigen-derived 30mer epitope elicits protection in BALB/c mice

EN Pompa-Mera, L Yepez-Mulia… - Experimental …, 2011 - Elsevier
Trichinellosis is a public health problem and is considered an emergent/re-emergent
disease in various countries. The etiological agent of trichinellosis is the nematode …

[HTML][HTML] A highly-safe live auxotrophic vaccine protecting against disease caused by non-typhoidal Salmonella Typhimurium in mice

P García, M Moscoso, V Fuentes-Valverde… - Journal of Microbiology …, 2023 - Elsevier
Abstract Background Salmonella enterica serovar Typhimurium (S. Typhimurium) has
become an important intestinal pathogen worldwide and is responsible for lethal invasive …