Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that predominantly
affects women of childbearing age and is characterized by the damage to multiple target …

Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer
patients is an unsolved issue. Here, we systematically analyzed the aberrant expression …

IL-37 was discovered as an anti-inflammatory and immunosuppressive cytokine of the IL-1
family. Significant advancements in the understanding of signaling pathways associated …

Introduction: Systemic lupus erythematosus [SLE] is a chronic, autoimmune condition
characterized by the formation of autoantibodies directed against nuclear components and …

Background Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease
affecting multiple organs and tissues with high cellular heterogeneity. CD8+ T cell activity is …

Objective B-cell activating factor (BAFF) is implicated in SLE pathogenesis. Blocking BAFF
signalling has contributed to reducing glucocorticoid dosage and preventing organ damage …

Women and men exhibit differences in innate and adaptive immunity, and women are more
susceptible to numerous autoimmune disorders. Two or more X chromosomes increases the …

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease
characterized by the involvement of multiple organs. Lupus nephritis (LN) is a major risk …

Systemic connective tissue disorders constitute a heterogenous group of autoimmune
diseases with the potential to affect a range of organs. Rheumatoid arthritis (RA) is a chronic …

B cells play a pivotal role in the pathogenesis of autoimmune disease (AD) by the production
of autoantibodies, secretion of cytokines and presentation of autoantigens. As a pro-survival …